Recombinant Anti-CTLA-4 × Anti-PD-1 Bispecific Antibody (Tandem Diabody) (CAT#: TAND-L001)

Recombinant Anti-CTLA-4 × Anti-PD-1 Bispecific Antibody (Tandem Diabody) is a bispecific fusion protein with four binding sites, two of which bind to antigens of one kind of cells and the other two to the other kind of cells. Tandem Diabodies do not carry Fc domains. So they are smaller than whole IgGs or IgG-derived BsAbs but larger than tandem scFvs. Therefore, they have a shorter serum half-life than IgGs but remain longer in the circulation compared with tandem scFvs. It was designed for the treatment of immunological rejective reaction.


Specific Inquiry
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  • Conjugation:
  • Datasheet
  • MSDS
  • COA

Specifications

  • Target
  • CTLA-4 & PD-1
  • Type
  • Tandem Diabody
  • Species Reactivity
  • Human
  • Target 1
  • CTLA-4
  • Host Species 1
  • Human
  • Target 2
  • PD-1
  • Host Species 2
  • Human
  • Application
  • FuncS, Promising therapeutic agent
  • Related Disease
  • Immunological rejective reaction

Target

  • Target 1
  • CTLA-4
  • Alternative Names
  • CTLA4; cytotoxic T-lymphocyte-associated protein 4; CD; GSE; GRD4; ALPS5; CD152; CTLA-4; IDDM12; CELIAC3; cytotoxic T-lymphocyte protein 4; CD152 isoform; celiac disease 3; insulin-dependent diabetes mellitus 12; cytotoxic T-lymphocyte-associated serine e
  • Target 2
  • PD-1
  • Alternative Names
  • PDCD1; programmed cell death 1; PD1; PD-1; CD279; SLEB2; hPD-1; hPD-l; hSLE1; programmed cell death protein 1; protein PD-1; systemic lupus erythematosus susceptibility 2

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For Research Use Only. Not For Clinical Use.

For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.

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