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Anti-EGFRvIII × Anti-CD3 Bispecific Antibody (TandAb, ABC 471) (TAND-LC015)

The anti-EGFRvIII/CD3 antibody is a TandAb which specifically targeting both EGFRvIII and CD3. By recruiting T cell and killing tumor cells, the tandem daibody can be potentially used in the treatment of solid tumor.      

Specifications
Targets
EGFRvIII & CD3
Type
TandAb
Expression Host
CHO
Species Reactivity
Human
Target 1
EGFRvIII
Host
Human
Clone
471
Target 2
CD3
Host
Human
Purity
>95% judged by SDS-PAGE under reducing condition
Applications
IHC, FC, WB, ELISA
Related Disease
Prostate cancer, Non-small-cell-lung cancer, Breast cancer
Targets
Target 1
EGFRvIII
Alternative Names
EGFRvIII; epidermal growth factor receptor variant III
Target 2
CD3
Alternative Names
CD3; CD3 T-Cell Co-receptor;CD3D; CD3E; CD3G

For lab research use only, not for diagnostic, therapeutic or any in vivo human use.

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