Products

Anti-EGFRvIII × Anti-CD3 Bi-specific T-cell engagers (BiTE, Human MR1-1×aCD3) (BITE-LC005)

The anti-CD3/EGFRvIII antibody specifically targets both CD3 and EGFRvIII. The bispecific antibody is a BiTE with highly antigen-specific. And by inducing high cytotoxicity on cancer cells, the BiTE can be potentially used in the treatent of cancers such as glioblastoma multiforme.      

Specifications
Targets
EGFRvIII & CD3
Type
BiTE
Expression Host
CHO
Species Reactivity
Human
Target 1
EGFRvIII
Host
Human
Clone
MR1-1
Target 2
CD3
Host
Human
Clone
huOKT3
Purity
>95% judged by SDS-PAGE under reducing condition
Applications
FC, ELISA
Related Disease
Glioblastoma multiforme
Targets
Target 1
EGFRvIII
Alternative Names
EGFRvIII; epidermal growth factor receptor variant III
Target 2
CD3
Alternative Names
CD3; CD3 T-Cell Co-receptor;CD3D; CD3E; CD3G

For lab research use only, not for diagnostic, therapeutic or any in vivo human use.

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