Products

Anti-EpCAM × Anti-CD3 Bispecific Antibody (BiTE, Adecatumumab) (BSAB-L001)

Recombinant Anti-EpCAM × Anti-CD3 Bi-specific T-cell engagers (BiTE) expressed as a single-chain Fv (scFv) from anti-EpCAM VH and VL region fused with a scFv of anti-CD3 VH and VL region with a His-tag at the C-terminus. This BsAb exists as a monomer under non-reducing and reducing condition. The complex is capable of targeting effector T cells to induce T-cell-mediated cytotoxicity of cells associated with a disease, such as Breast, prostate cancers.      

Specifications
Targets
EpCAM & CD3
Type
BiTE
Expression Host
CHO
Species Reactivity
Human
Target 1
EpCAM
Host
Human IgG1
Clone
adecatumumab
Target 2
CD3
Host
Mouse
Clone
OKT3
Purity
>95% judged by SDS-PAGE under reducing condition
Related Disease
Breast cance and prostate cancer
Targets
Target 1
EpCAM
Gene ID
4072
UniProt ID
P16422
Alternative Names
ESA; KSA; M4S1; MK-1; DIAR5; EGP-2; EGP40; KS1/4
Target 2
CD3
Alternative Names
CD3; cluster of differentiation 3; CD3γ; CD3δ; CD3ε; CD3ζ

For lab research use only, not for diagnostic, therapeutic or any in vivo human use.

Our customer service representatives are available 24 hours a day, from Monday to Sunday. Contact Us
Send Inquiry Now!
Name:
* Phone:
* E-mail Address:
* Service & Products Interested:
Project Description:
* Verification Code:
Please input "biolabs"(case insensitive) as verification code.
Contact Us to Order
Tel: 1-631-871-5806
Fax: 1-631-207-8356
Email:

45-1 Ramsey Road, Shirley, NY 11967, USA     Tel: 1-631-871-5806    Fax: 1-631-207-8356    Email:
Terms of Service-Privacy Policy     © 2007 - 2017 Creative-Biolabs All Rights Reserved