Products

Anti-FAP × Anti-CD3E Bi-specific T-cell engagers (BiTE, FA22D8HLxI2CHL) (BITE-LC015)

The anti-CD3/FAP antibody targets a T cell surface antigen CD3 and FAPalpha. The BiTE format bispecific antibody can induce T Cell mediated target cell lysis and therefore can be potentially used in the treatment of epithelial cancer.      

Specifications
Targets
FAP & CD3e
Type
BiTE
Expression Host
CHO
Species Reactivity
Human
Target 1
FAP
Host
Human
Clone
FA22D8
Target 2
CD3E
Host
Mouse
Clone
I2C
Purity
>95% judged by SDS-PAGE under reducing condition
Applications
FC, ELISA
Related Disease
Epithelial cancer
Targets
Target 1
FAP
Gene ID
2191
UniProt ID
B4DLR2
Alternative Names
FAP; fibroblast activation protein, alpha; FAPA; SIMP; DPPIV; prolyl endopeptidase FAP; seprase; FAPalpha
Target 2
CD3E
Gene ID
916
UniProt ID
P07766
Alternative Names
CD3E; CD3e molecule, epsilon (CD3-TCR complex); T3E; TCRE; IMD18; T-cell surface glycoprotein CD3 epsilon chain; CD3-epsilon; T-cell surface antigen T3/Leu-4 epsilon chain; CD3e antigen, epsilon polypeptide (TiT3 complex); T-cell antigen receptor complex, epsilon subunit of T3

For lab research use only, not for diagnostic, therapeutic or any in vivo human use.

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