Products

Anti-FcγRIII × Anti-CD30 Bispecific Antibody (TAND-L051)

Recombinant Anti-FcγRIII × Anti-CD30 Bispecific Antibody (TandAb) is a bispecific fusion protein with four binding sites, two of which bind to antigens of one kind of cells and the other two to the other kind of cells. This BsAb can retarget of NK cells to tumor cells. It was designed for the treatment of Hodgkin's disease.      

Specifications
Targets
FcγRIII & CD30
Type
TandAb
Expression Host
CHO
Species Reactivity
Human
Target 1
FcγRIII
Host
Mouse
Clone
3G8
Target 2
CD30
Host
Mouse
Clone
ARS-3
Purity
>95% judged by SDS-PAGE under reducing condition
Applications
FuncS, Promising therapeutic agent
Related Disease
Hodgkin's disease
Targets
Target 1
FcγRIII
Gene ID
2214
UniProt ID
M9MML0
Alternative Names
FCGR3A; Fc fragment of IgG, low affinity IIIa, receptor (CD16a); CD16; FCG3; CD16A; FCGR3; IGFR3; IMD20
Target 2
CD30
Gene ID
943
UniProt ID
A5D8T4
Alternative Names
TNFRSF8; tumor necrosis factor receptor superfamily, member 8; CD30; Ki-1; D1S166E; tumor necrosis factor receptor superfamily member 8; Ki-1 antigen; CD30L receptor; cytokine receptor CD30; lymphocyte activation antigen CD30

For lab research use only, not for diagnostic, therapeutic or any in vivo human use.

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