Recombinant Anti-FcγRI × Anti-CD33 Bispecific Antibody (CrossMab) (CAT#: CROSS-L030)
Recombinant Anti-FcγRI × Anti-CD33 Bispecific Antibody (CrossMab) has been generated by applying the Crossmab format to generate an IgG shaped entity that binds each ligand with one arm. This BsAb can retarget of monocytes to tumor cells. It was designed for the treatment of Acute myeloid leukemia (AML).
Specific Inquiry
Specifications
- Target
- FcγRI & CD33
- Type
- CrossMab
- Species Reactivity
- Human
- Target 1
- FcγRI
- Host Species 1
- Human
- Target 2
- CD33
- Host Species 2
- Human
- Application
- FuncS, Promising therapeutic agent
- Related Disease
- Acute myeloid leukemia (AML)
Target
- Target 1
- FcγRI
- Gene ID
- 2209
- UniProt ID
- P12314
- Alternative Names
- CD64; FCRI; CD64A; IGFR1
- Target 2
- CD33
- Gene ID
- 945
- UniProt ID
- P20138
- Alternative Names
- p67; SIGLEC3; SIGLEC-3
Downloads
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For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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