Products

Anti-GD2 × Anti-DTPA Bispecific Antibody (DVD-L016)

Recombinant Anti-GD2 × Anti-DTPA Bispecific Antibody (DVD-Ig) is comprised of a whole GD2-binding 'IgG' (with Fc region) and additional variable regions that bind DTPA fused 'on top' of the existing variable regions. This BsAb is capable of inhibiting signaling of their cognate receptors and a combined blockade of them has a greater inhibitory efficacy compared with inhibition of either factor alone. It was designed for the imaging and treatment of neuroblastoma and osteosarcoma.      

Specifications
Targets
GD2 & DTPA
Type
DVD-Ig
Expression Host
CHO
Species Reactivity
Human
Target 1
GD2
Host
Human
Target 2
DTPA
Host
Human
Purity
>95% judged by SDS-PAGE under reducing condition
Applications
FuncS, Pretargeting system for radioimaging and radiotherapy
Related Disease
Neuroblastoma and Osteosarcoma
Targets
Target 1
GD2
Alternative Names
Ganglioside G2; GD2; Ganglioside
Target 2
DTPA
Alternative Names
diethylenetriaminepentaacetic acid; DTPA

For lab research use only, not for diagnostic, therapeutic or any in vivo human use.

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