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Anti-GPC3 × Anti-CD3 Bi-specific T-cell engagers (BiTE, GPC3/CD3) (BITE-LC018)

The anti-CD3/GPC3 antibody is a BiTE targeting both a T cell surface antigen CD3 and GPC3. By mediating the tumor cell killing activity, the bispecific antibody can be potentially used in the treatment of cancers such as liver cancer.      

Specifications
Targets
GPC3 & CD3
Type
BiTE
Expression Host
CHO
Species Reactivity
Human
Target 1
GPC3
Host
Mouse
Clone
GC33
Target 2
CD3
Host
Mouse
Purity
>95% judged by SDS-PAGE under reducing condition
Applications
FC
Related Disease
Liver cancer
Targets
Target 1
GPC3
Gene ID
2719
UniProt ID
P51654
Alternative Names
GPC3; glypican 3; SGB; DGSX; MXR7; SDYS; SGBS; OCI-5
Target 2
CD3
Alternative Names
CD3; CD3 T-Cell Co-receptor;CD3D; CD3E; CD3G

For lab research use only, not for diagnostic, therapeutic or any in vivo human use.

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