Recombinant Anti-IL17 × Anti-TNF Bispecific Antibody (CrossMab) (CAT#: CROSS-L017)
Recombinant Anti-IL17 × Anti-TNFα Bispecific Antibody (CrossMab) has been generated by applying the Crossmab format to generate an IgGshaped entity that binds each ligand with one arm is capable of inhibiting signaling of their cognate receptors and a combined blockade of them has a greater inhibitory efficacy compared with inhibition of either factor alone. It was designed for the treatment of rheumatoid arthritis.
Specific Inquiry
Specifications
- Target
- IL17 & TNF
- Type
- CrossMab
- Species Reactivity
- Human
- Target 1
- IL17
- Host Species 1
- Human
- Target 2
- TNF
- Host Species 2
- Human
- Application
- FuncS, Promising therapeutic agent
- Related Disease
- Rheumatoid arthritis(RA)
Target
- Target 1
- IL17
- Gene ID
- 3605
- UniProt ID
- Q16552
- Alternative Names
- IL17A; interleukin 17A; IL17; CTLA8; IL-17; IL-17A; interleukin-17A; CTLA-8; cytotoxic T-lymphocyte-associated antigen 8; cytotoxic T-lymphocyte-associated protein 8; interleukin 17 (cytotoxic T-lymphocyte-associated serine esterase 8)
- Target 2
- TNF
- Gene ID
- 7124
- UniProt ID
- P01375
- Alternative Names
- TNF; tumor necrosis factor; DIF; TNFA; TNFSF2; TNF-alpha; TNF-a; cachectin; APC1 protein; TNF, monocyte-derived; TNF, macrophage-derived; tumor necrosis factor-alpha; tumor necrosis factor ligand superfamily member 2
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For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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