Products

Anti-IL4 × Anti-IL-13 Bispecific Antibody (BiTE, Dupilumab) (BSAB-L004)

Recombinant Anti-IL4 × Anti-IL-13 Bi-specific T-cell engagers (BiTE) expressed as a single-chain Fv (scFv) from anti-IL4 VH and VL region fused with a scFv of anti-IL-13 VH and VL region with a His-tag at the C-terminus. This BsAb exists as a monomer under non-reducing and reducing condition. It was designed for the treatment of Asthma, atopic dermatitis.      

Specifications
Targets
IL4 & IL-13
Type
BiTE
Expression Host
CHO
Species Reactivity
Human
Target 1
IL4
Host
Human IgG4 κ
Clone
dupilumab
Target 2
IL-13
Purity
>95% judged by SDS-PAGE under reducing condition
Related Disease
Asthma, atopic dermatitis
Targets
Target 1
IL4
Gene ID
3565
UniProt ID
P05112
Alternative Names
BSF1; IL-4; BCGF1; BSF-1; BCGF-1
Target 2
IL-13
Gene ID
3596
UniProt ID
P35225
Alternative Names
P600; IL-13

For lab research use only, not for diagnostic, therapeutic or any in vivo human use.

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