Recombinant Mouse Anti-MET × Anti-EGFR Bispecific Antibody (Triplebody) (CAT#: TRIAB-MZ007)
This bispecific antibody that specifically binds to human ErbB-1 and human c-Met comprises a first antigen-binding site that specifically binds to human ErbB-1 and a second antigen-binding site that specifically binds to human c-Met. It is capable of leading to a more pronounced inhibition of cancer cell proliferation and reducing the internalization of MET compared to the parent monospecific monovalent anti-c-Met antibody.
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Specifications
- Target
- MET & EGFR
- Type
- Triplebody
- Species Reactivity
- Human
- Target 1
- MET
- Host Species 1
- Human
- Target 2
- EGFR
- Host Species 2
- Human
- Application
- FC
- Related Disease
- Human ovary carcinoma
Target
- Target 1
- MET
- Gene ID
- 4233
- UniProt ID
- A0A024R759
- Alternative Names
- MET; MET proto-oncogene, receptor tyrosine kinase; HGFR; AUTS9; RCCP2; c-Met; hepatocyte growth factor receptor; SF receptor; HGF receptor; HGF/SF receptor; proto-oncogene c-Met; scatter factor receptor; tyrosine-protein kinase Met; met proto-oncogene tyrosine kinase
- Target 2
- EGFR
- Gene ID
- 1956
- UniProt ID
- P00533
- Alternative Names
- EGFR; epidermal growth factor receptor; ERBB; HER1; mENA; ERBB1; PIG61; NISBD2; proto-oncogene c-ErbB-1; cell growth inhibiting protein 40; erb-b2 receptor tyrosine kinase 1; cell proliferation-inducing protein 61; receptor tyrosine-protein kinase erbB-1; avian erythroblastic leukemia viral (v-erb-b) oncogene homolog
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Tandem Diabody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAND-L008 | Recombinant Anti-MET × Anti-EGFR Bispecific Antibody (Tandem Diabody) | FuncS, Promising therapeutic agent | Tandem Diabody |
Triplebody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TRIAB-MZ006 | Recombinant Anti-MET × Anti-EGFR Bispecific Antibody (Triplebody) | WB, ICC | Triplebody |
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For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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