Recombinant Anti-MET × Anti-EpCAM Bispecific Antibody (Tandem Diabody, Ab#5) (CAT#: TAND-MZ025)
This bispecific antibody can cause a more remarkable tumor regression compared to OA-5D5 which does not meaningfully slow tumor growth. It is also capable of binding to the cell surface receptors c-Met and EpCam as well as inhibiting signal transduction through the cell surface receptors.
Specific Inquiry
Specifications
- Target
- MET & EpCAM
- Type
- Tandem Diabody
- Species Reactivity
- Human
- Target 1
- MET
- Host Species 1
- Human
- Target 2
- EpCAM
- Host Species 2
- Human
- Application
- FuncS, Promising therapeutic agent
- Related Disease
- Lung cancer
Target
- Target 1
- MET
- Gene ID
- 4233
- UniProt ID
- A0A024R759
- Alternative Names
- MET; MET proto-oncogene, receptor tyrosine kinase; HGFR; AUTS9; RCCP2; c-Met; hepatocyte growth factor receptor; SF receptor; HGF receptor; HGF/SF receptor; proto-oncogene c-Met; scatter factor receptor; tyrosine-protein kinase Met; met proto-oncogene tyrosine kinase
- Target 2
- EpCAM
- Gene ID
- 4072
- UniProt ID
- P16422
- Alternative Names
- EPCAM; epithelial cell adhesion molecule; ESA; KSA; M4S1; MK-1; DIAR5; EGP-2; EGP40; KS1/4; MIC18; TROP1; EGP314; HNPCC8; TACSTD1; epithelial glycoprotein 314; human epithelial glycoprotein-2; cell surface glycoprotein Trop-1; adenocarcinoma-associated antigen; tumor-associated calcium signal transducer 1; major gastrointestinal tumor-associated protein GA733-2; membrane component, chromosome 4, surface marker (35kD glycoprotein)
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For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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