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Anti-MET × Anti-EpCAM Bispecific Antibody (TandAb, Ab#7) (TAND-MZ026)

This bispecific antibody can cause a more remarkable tumor regression compared to OA-5D5 which does not meaningfully slow tumor growth. It is also capable of binding to the cell surface receptors c-Met and EpCam as well as inhibiting signal transduction through the cell surface receptors.      

Specifications
Targets
MET & EpCAM
Type
TandAb
Expression Host
CHO
Species Reactivity
Human
Target 1
MET
Host
Human
Clone
OA-5D5
Target 2
EpCAM
Host
Human
Purity
>95% judged by SDS-PAGE under reducing condition
Applications
ELISA, WB
Related Disease
Lung cancer
Targets
Target 1
MET
Gene ID
4233
UniProt ID
A0A024R759
Alternative Names
MET; MET proto-oncogene, receptor tyrosine kinase; HGFR; AUTS9; RCCP2; c-Met; hepatocyte growth factor receptor; SF receptor
Target 2
EpCAM
Gene ID
4072
UniProt ID
P16422
Alternative Names
EPCAM; epithelial cell adhesion molecule; ESA; KSA; M4S1; MK-1; DIAR5; EGP-2; EGP40; KS1/4; MIC18; TROP1; EGP314; HNPCC8; TACSTD1; epithelial glycoprotein 314; human epithelial glycoprotein-2; cell surface glycoprotein Trop-1; adenocarcinoma-associated antigen; tumor-associated calcium signal transducer 1; major gastrointestinal tumor-associated protein GA733-2; membrane component, chromosome 4, surface marker (35kD glycoprotein)

For lab research use only, not for diagnostic, therapeutic or any in vivo human use.

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