Recombinant Anti-MUC1 × Anti-CD3 Bispecific Antibody (Fab2) (CAT#: FAB-L055)

Recombinant Anti-MUC1 × Anti-CD3 Bispecific Antibody (Fab2) is composed of the Fab of the anti-MUC1 monoclonal antibody and Fab of an antibody specific for CD3. A linker is added between the two Fab. The bispecific antibody is somewhat smaller than a whole IgG and therefore it clears from the blood naturally at a faster rate. This BsAb is capable of targeting the tumor and recruiting T effector cells via binding to the CD3 subunit of the T cell receptor complex. It was designed for the treatment of breast cancer.


Specific Inquiry
  • Size:
  • Conjugation:
  • Datasheet
  • MSDS
  • COA

Specifications

  • Target
  • MUC1 & CD3
  • Type
  • Fab2
  • Species Reactivity
  • Human
  • Target 1
  • MUC1
  • Host Species 1
  • Mouse
  • Target 2
  • CD3
  • Host Species 2
  • Mouse
  • Application
  • FuncS, Promising therapeutic agent
  • Related Disease
  • Breast cancer

Target

  • Target 1
  • MUC1
  • Alternative Names
  • MUC1; mucin 1, cell surface associated; EMA; MCD; PEM; PUM; KL-6; MAM6; MCKD; PEMT; CD227; H23AG; MCKD1; MUC-1; ADMCKD; ADMCKD1; CA 15-3; MUC-1/X; MUC1/ZD; MUC-1/SEC; mucin-1; episialin; DF3 antigen; H23 antigen; cancer antigen 15-3; krebs von den Lungen-
  • Target 2
  • CD3
  • Alternative Names
  • CD3E; CD3e molecule, epsilon (CD3-TCR complex); T3E; TCRE; IMD18; T-cell surface glycoprotein CD3 epsilon chain; CD3-epsilon; T-cell surface antigen T3/Leu-4 epsilon chain; CD3e antigen, epsilon polypeptide (TiT3 complex); T-cell antigen receptor complex, epsilon subunit of T3

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For Research Use Only. Not For Clinical Use.

For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.

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