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Anti-TPBG × Anti-CD3 Bi-specific T-cell engagers (BiTE, 5T4-4 LH × CD3 HL) (BITE-LC030)

The anti-CD3/5T4 antibody targets CD3 and 5T4. The BiTE bispecific antibody can be potentially used for treating colon carcinoma via induction of T cell cytotoxicity.      

Specifications
Targets
5T4 & CD3
Type
BiTE
Expression Host
CHO
Species Reactivity
Human
Target 1
5T4
Host
Human
Clone
5T4-4 scFv (LH)
Target 2
CD3
Host
Human
Purity
>95% judged by SDS-PAGE under reducing condition
Applications
FC
Related Disease
Colon carcinoma
Targets
Target 1
5T4
Gene ID
7162
UniProt ID
Q13641
Alternative Names
TPBG; trophoblast glycoprotein; 5T4; M6P1; 5T4AG; WAIF1; 5T4 oncofetal antigen; 5T4 oncotrophoblast glycoprotein
Target 2
CD3
Alternative Names
CD3; CD3 T-Cell Co-receptor;CD3D; CD3E; CD3G

For lab research use only, not for diagnostic, therapeutic or any in vivo human use.

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