Products

Anti-gpA33 × Anti-CD3 Bi-specific T-cell engagers (BITE-L045)

Recombinant Anti-gpA33 × Anti-CD3 Bi-specific T-cell engagers (BiTE) expressed as a single-chain Fv (scFv) from anti-gpA33 VH and VL region fused with a scFv of anti-CD3 VH and VL region with a His-tag at the C-terminus. This BsAb exists as a monomer under non-reducing and reducing condition. It is capable of targeting effector T cells to induce T-cell-mediated cytotoxicity of cells associated with a disease, such as non-Hodgkin lymphoma.      

Specifications
Targets
gpA33 & CD3
Type
BiTE
Expression Host
CHO
Species Reactivity
Human
Target 1
gpA33
Host
Mouse
Target 2
CD3
Host
Mouse
Clone
OKT3
Purity
>95% judged by SDS-PAGE under reducing condition
Applications
FuncS, Promising therapeutic agent
Related Disease
non-Hodgkin lymphoma
Targets
Target 1
gpA33
Gene ID
10223
UniProt ID
Q99795
Alternative Names
GPA33; glycoprotein A33 (transmembrane); A33; cell surface A33 antigen; transmembrane glycoprotein A33
Target 2
CD3
Gene ID
916
UniProt ID
P07766
Alternative Names
CD3E; CD3e molecule, epsilon (CD3-TCR complex); T3E; TCRE; IMD18; T-cell surface glycoprotein CD3 epsilon chain; CD3-epsilon; T-cell surface antigen T3/Leu-4 epsilon chain; CD3e antigen, epsilon polypeptide (TiT3 complex); T-cell antigen receptor complex, epsilon subunit of T3

For lab research use only, not for diagnostic, therapeutic or any in vivo human use.

Our customer service representatives are available 24 hours a day, from Monday to Sunday. Contact Us
Send Inquiry Now!
Name:
* Phone:
* E-mail Address:
* Service & Products Interested:
Project Description:
* Verification Code:
Please input "biolabs"(case insensitive) as verification code.
Contact Us to Order
Tel: 1-631-871-5806
Fax: 1-631-207-8356
Email:

45-1 Ramsey Road, Shirley, NY 11967, USA     Tel: 1-631-871-5806    Fax: 1-631-207-8356    Email:
Terms of Service-Privacy Policy     © 2007 - 2017 Creative-Biolabs All Rights Reserved