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Botulinum Toxin Type B (TP-065CL)

Neurotoxin produced by fermentation of clostridium botulinum type B. The protein exists in noncovalent association with hemagglutinin and nonhemagglutinin proteins as a neurotoxin complex. The neurotoxin complex is recovered from the fermentation process and purified through a series of precipitation and chromatography steps.      

Specifications
Classify
Protein therapeutics providing a novel function or activity: Enzymatic degradation of macromolecules
Therapeutic
Botulinum toxin type B
Trade Name
Myoblock
Function
Cleaves synaptobrevin at neuromuscular junctions to disrupt sNAre complex and prevent acetylcholine release, causing flaccid paralysis
Examples of Clinical Use
Many types of dystonia, particularly cervical; cosmetic uses
References
Synonyms
Botulinum neurotoxin type B precursor, BTX-B, RimabotulinumtoxinB
UniProt
P10844
Genbank
M81186

For lab research use only, not for diagnostic, therapeutic or any in vivo human use.

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