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CH2 domain anti-ERBB2 (SCH-L060)

The CH2 domain that bound Her2 was isolated from the library using phage display techonology. After affinity maturation, CH2 domain variants were identified having affinities (KD=10 nM) for Her2 as determined by biosensor technology. It's potential to be used in diagnostic, research and therapeutic applications.      

Specifications
Scaffold Name
CH2 domain
Origin
CH2 domain
Target
Her2
Species Reactivity
Human
Expression Host
E. coli
Affinity Constant
10 nM
Applications
ELISA; IHC; Microscopy; FC; WB; FuncS
Target
Alternative Names
CH2 domain; NEU; NGL; HER2; TKR1; CD340; HER-2; MLN 19
Entrez Gene ID
2064
UniProt ID
P04626

For lab research use only, not for diagnostic, therapeutic or any in vivo human use.

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