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CTLD anti-TNFRSF10B (SCl-L067)

The CTLD that bound DR5 was isolated from the library using phage display techonology. After affinity maturation, CTLD variants were identified having affinities (KD=5.74 nM) for DR5 as determined by biosensor technology. It's potential to be used in diagnostic, research and therapeutic applications.      

Specifications
Scaffold Name
CTLD
Origin
CTLD
Target
DR5
Species Reactivity
Human
Expression Host
E. coli
Affinity Constant
5.74 nM
Applications
ELISA; IHC; Microscopy; FC; WB; FuncS
Target
Alternative Names
CTLD; DR5; CD262; KILLER; TRICK2; TRICKB; ZTNFR9; TRAILR2
Entrez Gene ID
8795
UniProt ID
O14763

For lab research use only, not for diagnostic, therapeutic or any in vivo human use.

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