Products

Darbepoetin alfa (TP-029CL)

Human erythropoietin with 2 aa substitutions to enhance glycosylation (5 N-linked chains), 165 residues (MW=37 kD). Produced in Chinese hamster ovary (CHO) cells by recombinant DNA technology.      

Specifications
Classify
Protein therapeutics augmenting an existing pathway: Haematopoiesis
Therapeutic
Darbepoetin-α14
Trade Name
Aranesp
Function
Modified erythropoietin with longer half-life; stimulates red blood cell production in the bone marrow
Examples of Clinical Use
Treatment of anaemia in patients with chronic renal insufficiency and chronic renal failure (+/- dialysis)
References
Synonyms
Epoetin, Erythropoietin precursor
UniProt
P01588
Genbank
X02158

For lab research use only, not for diagnostic, therapeutic or any in vivo human use.

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