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Designed TPR proteins anti-HSP90AA1 (SDT-L081)

The Designed ankyrin repeat protein (DARPins) that bound Hsp90 peptide was isolated from the library using Rational design techonology. After affinity maturation, DARPins variants were identified having affinities (KD=4.5 μM) for Hsp90 peptide as determined by biosensor technology. It's potential to be used in diagnostic, research and therapeutic applications.      

Specifications
Scaffold Name
Designed TPR proteins
Origin
Tetratricopeptide (TPR) protein
Core Structure
α3 repeated
Target
Hsp90 peptide
Species Reactivity
Human
Expression Host
E. coli
Affinity Constant
4.5 μM
Applications
ELISA; IHC; Microscopy; FC; WB; FuncS
Target
Alternative Names
tetratricopeptide (TPR) protein; Designed TPR proteins; EL52; HSPN; LAP2; HSP86; HSPC1; HSPCA
Entrez Gene ID
3320
UniProt ID
P07900

For lab research use only, not for diagnostic, therapeutic or any in vivo human use.

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