Products

Enfuvirtide (TP-099CL)

Enfuvirtide is a 36 residue synthetic peptide that inhibits HIV-1 fusion with CD4 cells. It is an N-terminal acetylated, C-terminal amide. As an HIV fusion inhibitor, it is the first of a novel class of antiretroviral drugs used in combination therapy for the treatment of HIV-1 infection.      

Specifications
Classify
Protein therapeutics that interfere with a molecule or organism: Infectious diseases
Therapeutic
Enfuvirtide
Trade Name
Fuzeon
Function
36 amino-acid peptide that inhibits Hiv entry into host cells by binding to the Hiv envelope protein gp120/gp41
Examples of Clinical Use
Adults and children (at least 6 years old) with advanced Hiv infection
References
Synonyms
Envelope polyprotein GP160 precursor [Contains: Exterior membrane glycoprotein,GP120, Transmembrane glycoprotein,GP41]
UniProt
Q70626
Genbank
U12055

For lab research use only, not for diagnostic, therapeutic or any in vivo human use.

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