Etanercept (CAT#: TP-087CL)

Dimeric fusion protein consisting of the extracellular ligand-binding portion of the human 75 kilodalton (p75) tumor necrosis factor receptor (TNFR) linked to the Fc portion of human IgG1. The Fc component of etanercept contains the CH2 domain, the CH3 domain and hinge region, but not the CH1 domain of IgG1. Etanercept is produced by recombinant DNA technology in a Chinese hamster ovary (CHO) mammalian cell expression system. It consists of 934 amino acids


Specific Inquiry
  • Size:
  • Conjugation:
  • Gene Expression
  • Datasheet
  • MSDS
  • COA
Normal Tissue
RNA Expression

Specifications

  • Classify
  • Protein therapeutics that interfere with a molecule or organism: Immunoregulation
  • Therapeutic
  • Etanercept
  • Trade Name
  • Enbrel
  • Function
  • Dimeric fusion protein between recombinant soluble TNF receptor and Fc portion of human immunoglobulin G1
  • Examples of clinical use
  • Rheumatoid arthritis, polyarticular-course juvenile rheumatoid arthritis, psoriatic arthritis, ankylosing spondylitis, plaque psoriasis

References

  • Synonyms
  • CD120b, p75, p80 TNF-alpha receptor, TNF-R2, Tumor necrosis factor receptor 2, Tumor necrosis factor receptor superfamily member 1B precursor, Tumor necrosis factor receptor type II
  • UniProt
  • P20333
  • Genbank
  • M32315

Downloads

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See other products for "TNFRSF1B"

Blocking Antibody

CAT Product Name Application Type
NEUT-2154CQ Hamster Anti-Tnfrsf1b Recombinant Antibody (clone TR75-54.7) FC, IP, Block, WB, ELISA Hamster IgG

Rabbit Monoclonal Antibody

CAT Product Name Application Type
MOR-3615 Rabbit Anti-TNFRSF1B Recombinant Antibody (clone DS3615AB) WB, IHC, ICC, IP, FC Rabbit IgG

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For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.

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