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Fc fragment anti-ERBB2 (SFR-L260)

The Fc fragment that bound ERBB2 was isolated from the library using Phage display techonology. After affinity maturation, Fc fragment variants were identified having affinities for ERBB2 as determined by biosensor technology. It's potential to be used in diagnostic, research and therapeutic applications.      

Specifications
Scaffold Name
Fc fragment
Origin
Human IgG1
Core Structure
CH2 domain and a CH3 domain
Target
Her2
Species Reactivity
Human
Expression Host
E. coli
Affinity Constant
10 nM
Applications
ELISA; IHC; Microscopy; FC; WB; FuncS
Target
Alternative Names
NEU; NGL; HER2; TKR1; CD340; HER-2; MLN 19; HER-2/neu
Entrez Gene ID
2064
UniProt ID
P04626

For lab research use only, not for diagnostic, therapeutic or any in vivo human use.

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