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HPSTI anti-ELANE (SHP-L252)

The HPSTI that bound Neutrophil elastase was isolated from the library using Phage display; techonology. After affinity maturation, HPSTI variants were identified having affinities for Neutrophil elastase as determined by biosensor technology. It's potential to be used in diagnostic, research and therapeutic applications.      

Specifications
Scaffold Name
HPSTI
Origin
Human pancreatic secretory trypsin inhibitor (PSTI)
Core Structure
α/β-loops (56)
Variable Regions
6 to 8 aa
Target
Neutrophil elastase
Species Reactivity
Human
Expression Host
BL21 (DE3) cells
Applications
ELISA; IHC; Microscopy; FC; WB; FuncS
Target
Alternative Names
human pancreatic secretory trypsin inhibitor (PSTI); HPSTI; GE; NE; HLE; HNE; ELA2; SCN1
Entrez Gene ID
1991
UniProt ID
P08246

For lab research use only, not for diagnostic, therapeutic or any in vivo human use.

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