Products

Immune Globulin Human (TP-026CL)

Intravenous immunoglobulin (IVIg) is a mixture of IgG1 and other antibodies derived from healthy human plasma via Cohn fractionation. The purification process includes cold alcohol fractionation, polyethylene glycol precipitation, and ion exchange chromatography. IVIg contains the same distribution of IgG antibody subclasses as is found in the general human population. IgG subclasses are fully represented in the following proportions: 70.3% IgG1, 24.7% IgG2, 3.1% IgG3, and 1.9% IgG4. IVIg is used in the treatment of immunodeficiencies, as well as autoimmune and inflammatory disorders.      

Specifications
Classify
Protein therapeutics replacing a protein that is deficient or abnormal: Immunodeficiencies
Therapeutic
Pooled immunoglobulins
Trade Name
Octagam
Function
Intravenous immunoglobulin preparation
Examples of Clinical Use
Primary immunodeficiencies
References
Synonyms
Human IGG, Human Immunoglobulin G, Human Normal Immunoglobulin, Immune globulin (human), Immune Globulin Intravenous, Immune Globulin Subcutaneous, Immunoglobulin G, Human, Intravenous Immunoglobulin, IVIg
UniProt
P01877
Genbank
J00221

For lab research use only, not for diagnostic, therapeutic or any in vivo human use.

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