Interferon gamma-1b (CAT#: TP-045CL)
Human Interferon gamma-1b (140 residues), produced from E. coli. Production of Actimmune is achieved by fermentation of a genetically engineered Escherichia coli bacterium containing the DNA which encodes for the human protein. Purification of the product is achieved by conventional column chromatography.
The sequence displayed is a cDNA sequence which codes for human interferon gamma, as described by Gray et. al. and not specifically interferon gamma 1b.
Normal Tissue
RNA Expression
Figure 1 Colon
(Endothelial cells
Staining: Medium
Intensity: Moderate
Quantity:>75%
Location: Cytoplasmic/membranous
Glandular cells
Staining: Medium
Intensity: Moderate
Quantity:>75%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/10344/26961_A_8_3.jpg
(Endothelial cells
Staining: Medium
Intensity: Moderate
Quantity:>75%
Location: Cytoplasmic/membranous
Glandular cells
Staining: Medium
Intensity: Moderate
Quantity:>75%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/10344/26961_A_8_3.jpg
Figure 2 RNA cell line category: Not detected
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000111537-IFNG
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000111537-IFNG
Figure 2 RNA cell line category: Not detected
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000111537-IFNG
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000111537-IFNG
Specifications
- Classify
- Protein therapeutics augmenting an existing pathway: Immunoregulation
- Therapeutic
- Interferon-γ1b (IFNγ)
- Trade Name
- Actimmune
- Function
- Increases inflammatory and antimicrobial response
- Examples of clinical use
- Chronic granulomatous disease, severe osteopetrosis
References
- Synonyms
- IFN-gamma, Immune interferon, Interferon gamma precursor
- UniProt
- P01579
- Genbank
- X13274
Related Resources
Inflammatory Bowel Diseases
Rheumatoid Arthritis
Systemic Lupus Erythematosus
Primary Immunodeficiency
Maturity Onset Diabetes of the Young
Downloads
Download resources about recombinant antibody development and antibody engineering to boost your research.
See other products for "IFNG"
Single-domain Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| NABL-090 | Recombinant Anti-human IFNG VHH Single Domain Antibody | WB, ELISA, IHC, FC, FuncS | Llama VHH |
| TAB-140CT | Anti-Human IFN-γ Therapeutic Single Domain Antibody (BIV 3E) | ELISA | Single domain antibody |
| TAB-141CT | Anti-Human IFN-γ Therapeutic Single Domain Antibody (TRI 3E) | ELISA | Single domain antibody |
| TAB-142CT | Anti-Human IFN-γ Therapeutic Single Domain Antibody (TETRA 3E) | ELISA | Single domain antibody |
| TAB-143CT | Anti-Human IFN-γ Therapeutic Single Domain Antibody (BIV#m3F) | ELISA | Single domain antibody |
Humanized Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-041 | Anti-Human IFNG Recombinant Antibody (Fontolizumab) | IP, IF, FuncS, FC, Neut, ELISA, IHC | IgG1 |
| PABX-113 | Recombinant Human Anti-IFN-gamma Antibody (HuZAF) | WB, ELISA, FuncS | IgG |
| PABX-113-F (E) | Recombinant Human Anti-IFN-gamma Antibody Fab Fragment (HuZAF) | WB, ELISA, FuncS | Fab |
scFv Fragment Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| PSBL-229 | Human Anti-IFNG Recombinant Antibody (clone YC118); scFv Fragment | WB, ELISA, FuncS | Human scFv |
| FAMAB-0176-YC-S(P) | Mouse Anti-IFNG Recombinant Antibody (clone D9DlO); scFv Fragment | ELISA, WB | Mouse scFv |
| HPAB-S0067-YC-S(P) | Human Anti-IFNG Recombinant Antibody (clone chAF2); scFv Fragment | ELISA, Neut | Mouse scFv |
| HPAB-S0068-YC-S(P) | Human Anti-IFNG Recombinant Antibody (clone Haf25); scFv Fragment | ELISA, Neut | Humanized scFv |
| HPAB-S0069-YC-S(P) | Human Anti-IFNG Recombinant Antibody (clone HuXAF); scFv Fragment | ELISA, Neut | Humanized scFv |
Fab Fragment Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| PFBL-229 | Human Anti-IFNG Recombinant Antibody (clone YC118); Fab Fragment | WB, ELISA, FuncS | Human Fab |
| FAMAB-0162-CN-F(E) | Human Anti-IFNG Recombinant Antibody (clone 41ms4G); Fab Fragment | ELISA | Human Fab |
| FAMAB-0163-CN-F(E) | Human Anti-IFNG Recombinant Antibody (clone 57-5); Fab Fragment | ELISA | Human Fab |
| FAMAB-0164-CN-F(E) | Human Anti-IFNG Recombinant Antibody (clone 36-4); Fab Fragment | ELISA | Human Fab |
| FAMAB-0165-CN-F(E) | Human Anti-IFNG Recombinant Antibody (clone 44ms4); Fab Fragment | ELISA | Human Fab |
Mouse Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-0289MC | Recombinant Anti-Canine IFN-gamma Antibody. | WB, ELISA |
Human Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| PABX-112 | Recombinant Human Anti-IFN Antibody (ScFv01) | Neut, FuncS | IgG |
| PABX-112-S (P) | Recombinant Human Anti-IFN Antibody scFv Fragment (ScFv01) | Neut, FuncS | scFv |
| PABX-113-S (P) | Recombinant Human Anti-IFN-gamma Antibody scFv Fragment (HuZAF) | WB, ELISA, FuncS | scFv |
| PABX-112-F (E) | Recombinant Human Anti-IFN Antibody Fab Fragment (ScFv01) | Neut, FuncS | Fab |
| TAB-423CQ | Anti-Human IFNG Recombinant Antibody (Emapalumab) | ELISA, IHC, FC, IP, IF, FuncS | IgG1, λ1 |
Neutralizing Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| NEUT-992CQ | Mouse Anti-IFNG Recombinant Antibody (clone CBL766) | Neut | Mouse IgG1 |
| NEUT-993CQ | Mouse Anti-IFNG Recombinant Antibody (clone CBL813) | FC, CyTOF, Neut | Mouse IgG2b |
| NEUT-994CQ | Mouse Anti-IFNG Recombinant Antibody (clone 4S.B3) | FC, Neut | Mouse IgG |
| NEUT-995CQ | Mouse Anti-IFNG Recombinant Antibody (clone 7H58) | FC, IHC-Fr, Neut | Mouse IgG2 |
| NEUT-996CQ | Mouse Anti-IFNG Recombinant Antibody (clone CBL201) | ELISA, Neut | Mouse IgG1, κ |
Blocking Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| NEUT-1002CQ | Mouse Anti-IFNG Recombinant Antibody (clone CBL253) | Inhib, IHC, IP | Mouse IgG1 |
| NEUT-1008CQ | Mouse Anti-IFNG Recombinant Antibody (clone B133.5) | Block | Mouse IgG1 |
| NEUT-1013CQ | Mouse Anti-IFNG Recombinant Antibody (clone B-B1) | Block, FC | Mouse IgG1 |
| NEUT-1014CQ | Mouse Anti-IFNG Recombinant Antibody (clone D9D10) | Block, FC, ELISA, WB | Mouse IgG1 |
| NEUT-1033CQ | Mouse Anti-IFNG Recombinant Antibody (clone SN-6) | ELISA, Block | Mouse IgG1, κ |
Rabbit Monoclonal Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOR-1742 | Rabbit Anti-IFNG Recombinant Antibody (clone DS1742AB) | WB | Rabbit IgG |
| MOR-4228 | Rabbit Anti-IFNG Recombinant Antibody (clone SI307DS) | FC | Rabbit IgG |
| MOR-4600 | Rabbit Anti-IFNG Recombinant Antibody (clone TH113DS) | WB | Rabbit IgG |
| MOR-4601 | Rabbit Anti-IFNG Recombinant Antibody (clone TH114DS) | WB | Rabbit IgG |
| MOR-4602 | Rabbit Anti-Ifng Recombinant Antibody (clone TH115DS) | WB | Rabbit IgG |
Epitope-Specific Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| EPAF-0882LC | Mouse Anti-IFNG Recombinant Antibody (clone MIF3009) | ELISA | Mouse IgG1 |
Recombinant Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-083CQ | Mouse Anti-IFNG Recombinant Antibody (clone YC117) | FC | Mouse IgG2b |
| MOB-084CQ | Mouse Anti-IFNG Recombinant Antibody (clone YC116) | ELISA, FC | Mouse IgG1 |
| MOB-085CQ | Rabbit Anti-Guinea Pig IFNG Polyclonal Antibody | ICC, IHC, WB, IP | Rabbit IgG |
| MOB-083LC | Mouse Anti-IFNG Recombinant Antibody (clone YC114) | FC, IP, WB | Mouse IgG |
| FAMAB-0162-CN | Human Anti-IFNG Recombinant Antibody (clone 41ms4G) | ELISA | Human IgG |
ADCC Enhanced Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| AFC-TAB-041 | Afuco™ Anti-IFNG ADCC Recombinant Antibody (Fontolizumab), ADCC Enhanced | IP, IF, FuncS, FC, Neut, ELISA | ADCC enhanced antibody |
| AFC-TAB-423CQ | Afuco™ Anti-IFNG ADCC Recombinant Antibody (Emapalumab), ADCC Enhanced | ELISA, IHC, FC, IP, IF, FuncS | ADCC enhanced antibody |
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For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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