Kunitz domains scaffold protein anti-Human αvβ5 integrin (CAT#: SKD-L095)

The Kunitz domain that bound αvβ5 integrin was isolated from the library using phage display techonology. Kunitz domains are stable as standalone peptides, able to recognise specific protein structures, and also work as competitive protease inhibitors in their free form. After affinity maturation, Kunitz domains variants were identified having affinities for αvβ5 integrin as determined by biosensor technology. It's potential to be used in diagnostic, research and therapeutic applications.


Specific Inquiry
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Specifications

  • Scaffold Name
  • Kunitz domains
  • Origin
  • Knottin protein
  • Variable Regions
  • 9-13 amino acids
  • Target
  • αvβ5 integrin
  • Species Reactivity
  • Human
  • Expression Host
  • E. coli
  • Applications
  • ELISA; IHC; Microscopy; FC; WB; FuncS

Target

  • Alternative Names
  • knottin protein; Kunitz domains; αvβ5 integrin; αvβ5; integrin

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For Research Use Only. Not For Clinical Use.

For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.

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