Kunitz domains scaffold protein anti-Human Factor Xia (CAT#: SKD-L098)

The Kunitz domain that bound Factor Xia was isolated from the library using phage display techonology. Kunitz domains are stable as standalone peptides, able to recognise specific protein structures, and also work as competitive protease inhibitors in their free form. After affinity maturation, Kunitz domains variants were identified having affinities for Factor Xia as determined by biosensor technology. It's potential to be used in diagnostic, research and therapeutic applications.


Specific Inquiry
  • Size:
  • Conjugation:
  • Gene Expression
  • Datasheet
  • MSDS
  • COA
Subcellular Location
RNA Expression

Specifications

  • Scaffold Name
  • Kunitz domains
  • Origin
  • APPI
  • Core Structure
  • α-helices, β-sheets
  • Variable Regions
  • 1–2 Loops
  • Target
  • Factor Xia
  • Species Reactivity
  • Human
  • Expression Host
  • E. coli
  • Applications
  • ELISA; IHC; Microscopy; FC; WB; FuncS

Target

  • Alternative Names
  • APPI; Kunitz domains; FXI

Downloads

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For Research Use Only. Not For Clinical Use.

For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.

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