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Kunitz domains anti-F7 (SKD-L097)

The Kunitz domain that bound Factor VIIa was isolated from the library using phage display techonology. Kunitz domains are stable as standalone peptides, able to recognise specific protein structures, and also work as competitive protease inhibitors in their free form. After affinity maturation, Kunitz domains variants were identified having affinities for Factor VIIa as determined by biosensor technology. It's potential to be used in diagnostic, research and therapeutic applications.      

Specifications
Scaffold Name
Kunitz domains
Origin
APPI
Core Structure
α-helices, β-sheets
Variable Regions
1–2 Loops
Target
Factor VIIa
Species Reactivity
Human
Expression Host
E. coli
Applications
ELISA; IHC; Microscopy; FC; WB; FuncS
Target
Alternative Names
APPI; Kunitz domains; SPCA
Entrez Gene ID
2155
UniProt ID
P08709

For lab research use only, not for diagnostic, therapeutic or any in vivo human use.

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