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LDTI anti-F2 (SLD-L120)

The LDTI that bound Thrombin was isolated from the library using Phage display techonology. After affinity maturation, LDTI variants were identified having affinities (KD=28 nM) for Thrombin as determined by biosensor technology. It's potential to be used in diagnostic, research and therapeutic applications.      

Specifications
Scaffold Name
LDTI
Origin
Leech-derived tryptase inhibitor (LDTI)
Core Structure
α/β (46)
Variable Regions
5 aa
Target
Thrombin
Species Reactivity
Human
Expression Host
E. coli
Affinity Constant
28 nM
Applications
ELISA; IHC; Microscopy; FC; WB; FuncS
Target
Alternative Names
leech-derived tryptase inhibitor (LDTI); LDTI; PT; THPH1; RPRGL2
Entrez Gene ID
2147
UniProt ID
P00734

For lab research use only, not for diagnostic, therapeutic or any in vivo human use.

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