Products

Lepirudin (TP-074CL)

Lepirudin is identical to natural hirudin except for substitution of leucine for isoleucine at the N-terminal end of the molecule and the absence of a sulfate group on the tyrosine at position 63. It is produced via yeast cells. Bayer ceased the production of lepirudin (Refludan) effective May 31, 2012.      

Specifications
Classify
Protein therapeutics providing a novel function or activity: Haemostasis and thrombosis
Therapeutic
Lepirudin
Trade Name
Refludan
Function
Recombinant hirudin, a thrombin inhibitor from the salivary gland of the medicinal leech Hirudo medicinalis
Examples of Clinical Use
Heparin-induced thrombocytopaenia
References
Synonyms
Hirudin variant-1, Lepirudin recombinant
UniProt
P01050

For lab research use only, not for diagnostic, therapeutic or any in vivo human use.

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