Products

Lutropin alfa (TP-036CL)

Lutropin alfa is a recombinant human luteinizing hormone produced in yeast with 2 subunits, alpha = 92 residues, beta = 121 residues. It is a heterodimeric glycoprotein. Each monomeric unit is a glycoprotein molecule. In females, an acute rise of LH ("LH surge") triggers ovulation and the development of the corpus luteum. In males, it stimulates Leydig cell production of testosterone. Lutropin alfa was the first and only recombinant human form of luteinizing hormone (LH) developed for use in the stimulation of follicular development.      

Specifications
Classify
Protein therapeutics augmenting an existing pathway: Fertility
Therapeutic
Lutropin-α
Trade Name
Luveris
Function
Recombinant human luteinizing hormone; increases estradiol secretion, thereby supporting follicle-stimulating hormone-induced follicular development
Examples of Clinical Use
Infertility with luteinizing hormone deficiency
References
Synonyms
ICSH, Insterstiial cell-stimulating hormone, LH, LH-B, LSH- beta, LSH-B, Luteinizing hormone, Luteinizing hormone beta subunit, Lutrophin, Lutropin alpha, Lutropin beta chain precursor
UniProt
P01229
Genbank
X00264

For lab research use only, not for diagnostic, therapeutic or any in vivo human use.

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