Products

Omalizumab (TP-097CL)

A recombinant DNA-derived humanized IgG1k monoclonal antibody that selectively binds to human immunoglobulin E (IgE). omalizumab is produced by a Chinese hamster ovary cell suspension culture in a nutrient medium containing the antibiotic gentamicin.      

Specifications
Classify
Protein therapeutics that interfere with a molecule or organism: Pulmonary disorders
Therapeutic
Omalizumab
Trade Name
omalizumab
Function
Humanized mAb that inhibits ige binding to the high-affinity ige receptor on mast cells and basophils, decreasing activation of these cells and release of inflammatory mediators
Examples of Clinical Use
Adults and adolescents (at least 12 years old) with moderate to severe persistent asthma who have a positive skin test or in vitro reactivity to a perennial aeroallergen and whose symptoms are inadequately controlled with inhaled corticosteroids
References
Synonyms
Ig gamma-1 chain C region
UniProt
P01857
Genbank
J00228

For lab research use only, not for diagnostic, therapeutic or any in vivo human use.

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