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PDZ domain scaffold protein anti-Human EFNB2 (CAT#: SPD-L159)

The PDZ domain that bound EFNB2 was isolated from the library using phage display techonology. PDZ domains are modular protein-interaction domains that are specialized for binding to short peptide motifs at the extreme carboxy (C) termini of other proteins, athough they can also have other modes of interaction. After affinity maturation, PDZ domain variants were identified having affinities for EFNB2 as determined by biosensor technology. It's potential to be used in diagnostic, research and therapeutic applications.


See more Antibody-like Scaffold Protein products for EFNB2
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  • Conjugation:
  • Gene Expression
  • Datasheet
  • MSDS
  • COA
Subcellular Location
Figure 1 IF staining of human cell line U-2 OS
Figure 1 IF staining of human cell line U-2 OS
(Immunofluorescent staining of human cell line U-2 OS shows localization to nucleoplasm & cytosol.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/8999/47_A4_1_selected.jpg
Figure 2 IF staining of human cell line U-251 MG
Figure 2 IF staining of human cell line U-251 MG
(Immunofluorescent staining of human cell line U-251 MG shows localization to nucleoplasm & cytosol.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/9368/if_selected.jpg
Normal Tissue
Figure 3 IHC staining of human kidney
Figure 3 IHC staining of human kidney
(Immunohistochemical staining of human kidney shows moderate cytoplasmic positivity in cells in tubules and cells in glomeruli.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/8999/26099_A_8_5_selected.jpg
Figure 4 Cerebral cortex
Figure 4 Cerebral cortex
(Endothelial cells
Staining: Medium
Intensity: Moderate
Quantity:>75%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/8999/26099_B_7_5.jpg
Figure 5 Colon
Figure 5 Colon
(Endothelial cells
Staining: Medium
Intensity: Moderate
Quantity:>75%
Location: Cytoplasmic/membranous
Glandular cells
Staining: Medium
Intensity: Moderate
Quantity:>75%
Location: Cytoplasmic/membranous
Peripheral nerve/ganglion
Staining: Medium
Intensity: Moderate
Quantity:>75%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/8999/26099_A_9_3.jpg
Figure 6 Liver
Figure 6 Liver
(Hepatocytes
Staining: Medium
Intensity: Moderate
Quantity:>75%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/8999/26099_A_8_4.jpg
Figure 7 Kidney
Figure 7 Kidney
(Cells in glomeruli
Staining: Medium
Intensity: Moderate
Quantity:>75%
Location: Cytoplasmic/membranous
Cells in tubules
Staining: Medium
Intensity: Moderate
Quantity:>75%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/8999/26099_A_7_5.jpg
Figure 8 Testis
Figure 8 Testis
(Leydig cells
Staining: Medium
Intensity: Moderate
Quantity:>75%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/8999/26099_A_5_6.jpg
Figure 9 Skin
Figure 9 Skin
(Endothelial cells
Staining: Medium
Intensity: Moderate
Fibrohistiocytic cells
Staining: Medium
Intensity: Moderate
Lymphocytes
Staining: Medium
Intensity: Moderate)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/8999/26099_B_7_1.jpg
RNA Expression
Figure 10 RNA cell line category: Cell line enhanced (AF22, OE19, SH-SY5Y)
Figure 10 RNA cell line category: Cell line enhanced (AF22, OE19, SH-SY5Y)
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000125266-EFNB2

Specifications

  • Scaffold Name
  • PDZ domain
  • Origin
  • PSD-95 protein
  • Core Structure
  • β-sheet
  • Target
  • EFNB2
  • Species Reactivity
  • Human
  • Expression Host
  • E. coli
  • Applications
  • ELISA; IHC; Microscopy; FC; WB; FuncS

Target

  • Alternative Names
  • PSD-95 protein; PDZ domain; HTKL; EPLG5; Htk-L; LERK5

Downloads

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See other products for "EFNB2"

scFv Fragment Antibody

CAT Product Name Application Type
MOB-304-S(P) Recombinant Anti-human EFNB2 Antibody scFv Fragment IF, Neut, FuncS scFv
HPAB-0164-LSX-S(P) Human Anti-EFNB2 Recombinant Antibody (clone A11); scFv Fragment ELISA Human scFv
HPAB-0165-LSX-S(P) Human Anti-EFNB2 Recombinant Antibody (clone B1); scFv Fragment ELISA Human scFv
HPAB-0166-LSX-S(P) Human Anti-EFNB2 Recombinant Antibody (clone D1); scFv Fragment ELISA Human scFv
HPAB-0167-LSX-S(P) Human Anti-EFNB2 Recombinant Antibody (clone E2); scFv Fragment ELISA Human scFv

Recombinant Antibody

CAT Product Name Application Type
MHH-304 Recombinant Human Anti-human EFNB2 Antibody WB, IHC, FuncS IgG
HPAB-0164-LSX Human Anti-EFNB2 Recombinant Antibody (clone A11) ELISA Human IgG
HPAB-0165-LSX Human Anti-EFNB2 Recombinant Antibody (clone B1) ELISA Human IgG
HPAB-0166-LSX Human Anti-EFNB2 Recombinant Antibody (clone D1) ELISA Human IgG
HPAB-0167-LSX Human Anti-EFNB2 Recombinant Antibody (clone E2) ELISA Human IgG

Fab Fragment Antibody

CAT Product Name Application Type
MHH-304-F(E) Recombinant Human Anti-human EFNB2 Antibody Fab Fragment ELISA, IP, FuncS Fab
HPAB-0164-LSX-F(E) Human Anti-EFNB2 Recombinant Antibody (clone A11); Fab Fragment ELISA Human Fab
HPAB-0165-LSX-F(E) Human Anti-EFNB2 Recombinant Antibody (clone B1); Fab Fragment ELISA Human Fab
HPAB-0166-LSX-F(E) Human Anti-EFNB2 Recombinant Antibody (clone D1); Fab Fragment ELISA Human Fab
HPAB-0167-LSX-F(E) Human Anti-EFNB2 Recombinant Antibody (clone E2); Fab Fragment ELISA Human Fab

Human Antibody

CAT Product Name Application Type
TAB-389MZ Anti-Human EFNB2 Recombinant Antibody (2B1) Block, FuncS, Inhib, WB Human antibody
TAB-390MZ Anti-Human EFNB2 Recombinant Antibody (B11) Block, FuncS, Inhib, WB Human antibody
TAB-391MZ Anti-Human EFNB2 Recombinant Antibody (A1) ELISA Human antibody
TAB-392MZ Anti-Human EFNB2 Recombinant Antibody (E4 ) ELISA Human antibody
TAB-395MZ Anti-Human EFNB2 Recombinant Antibody (31.19.2D3) IHC, ELISA Human antibody

Rabbit Monoclonal Antibody

CAT Product Name Application Type
MOR-1100 Hi-Affi™ Rabbit Anti-EFNB2 Recombinant Antibody (clone DS1100AB) WB, ICC, IF Rabbit IgG

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For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.

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