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PDZ domain anti-PTEN (SPD-L152)

The PDZ domain that bound PTEN was isolated from the library using phage display techonology. PDZ domains are modular protein-interaction domains that are specialized for binding to short peptide motifs at the extreme carboxy (C) termini of other proteins, athough they can also have other modes of interaction. After affinity maturation, PDZ domain variants were identified having affinities for PTEN as determined by biosensor technology. It's potential to be used in diagnostic, research and therapeutic applications.      

Specifications
Scaffold Name
PDZ domain
Origin
MAGI-2 (membrane associated guanylate kinase inverted-2)
Target
PTEN
Species Reactivity
Human
Expression Host
BL21 (DE3) cells
Applications
ELISA; IHC; Microscopy; FC; WB; FuncS
Target
Alternative Names
MAGI-2 (membrane associated guanylate kinase inverted-2); PDZ domain; BZS; DEC; CWS1; GLM2; MHAM; TEP1
Entrez Gene ID
5728
UniProt ID
P60484

For lab research use only, not for diagnostic, therapeutic or any in vivo human use.

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