PE-A*02:01/Human CTNNB1 (GLLGTLVQL) MHC Tetramer (CAT#: MHC-LC1978)

This product is a tetramer of biotinylated peptide/MHC complex with streptavidin mainly composed of human CTNNB1 of peptide GLLGTLVQL covering 400-408 and A*02:01 molecule. The pMHC tetramer recognizes CD8 T cells, and can be used in the analysis of individual antigen-specific T cells.


Specific Inquiry
  • Size:
  • Gene Expression
  • Datasheet
  • MSDS
  • COA
Subcellular Location
Normal Tissue
RNA Expression

Specifications

  • Allele
  • A*02:01
  • Class
  • Class I
  • Antigen
  • CTNNB1
  • Antigen Species
  • Human
  • Peptide
  • GLLGTLVQL
  • Range
  • 400-408
  • Conjugate
  • PE
  • Application
  • FCM

Target

  • Antigen Introduction
  • The protein encoded by this gene is part of a complex of proteins that constitute adherens junctions (AJs). AJs are necessary for the creation and maintenance of epithelial cell layers by regulating cell growth and adhesion between cells. The encoded protein also anchors the actin cytoskeleton and may be responsible for transmitting the contact inhibition signal that causes cells to stop dividing once the epithelial sheet is complete. Finally, this protein binds to the product of the APC gene, which is mutated in adenomatous polyposis of the colon. Mutations in this gene are a cause of colorectal cancer (CRC), pilomatrixoma (PTR), medulloblastoma (MDB), and ovarian cancer. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2016]
  • Alternative Names
  • CTNNB1; Catenin beta-1; CTNNB; MRD19; armadillo

Related Resources

  • Related Diseases

Downloads

Download resources about recombinant antibody development and antibody engineering to boost your research.

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Rabbit Monoclonal Antibody

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For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.

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