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PE-A*11:01/Human hP (MSLQRQFLR) MHC Tetramer (CAT#: MHC-LC2816)

This product is a tetramer of biotinylated peptide/MHC complex with streptavidin mainly composed of human hP of peptide MSLQRQFLR and A*11:01 molecule. The pMHC tetramer recognizes CD8 T cells, and can be used in the analysis of individual antigen-specific T cells.


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  • Gene Expression
  • Datasheet
  • MSDS
  • COA
Subcellular Location
Figure 1 IF staining of human cell line Hep G2
Figure 1 IF staining of human cell line Hep G2
(Immunofluorescent staining of human cell line Hep G2 shows localization to nucleoplasm & vesicles.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/47750/1309_F11_1_selected.jpg
Figure 2 IHC staining of human liver
Figure 2 IHC staining of human liver
(Immunohistochemical staining of human liver shows strong cytoplasmic positivity in hepatocytes.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/47750/ihc_selected.jpg
Figure 3 IHC staining of human testis
Figure 3 IHC staining of human testis
(Immunohistochemical staining of human testis shows strong cytoplasmic positivity in cells in seminiferous ducts.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/66795/170921_A_6_6_selected.jpg
Figure 4 IF staining of human cell line HeLa
Figure 4 IF staining of human cell line HeLa
(Immunofluorescent staining of human cell line HeLa shows localization to nucleoplasm.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/47750/788_B12_1_red_green.jpg
Normal Tissue
Figure 5 Liver
Figure 5 Liver
(Hepatocytes
Staining: High
Intensity: Strong
Quantity:>75%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/47750/118508_A_9_4.jpg
RNA Expression
Figure 6 RNA cell line category: Group enriched (Hep G2, HSkMC)
Figure 6 RNA cell line category: Group enriched (Hep G2, HSkMC)
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000257017-HP
Figure 6 RNA cell line category: Group enriched (Hep G2, HSkMC)
Figure 6 RNA cell line category: Group enriched (Hep G2, HSkMC)
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000257017-HP

Specifications

  • Allele
  • A*11:01
  • Class
  • Class I
  • Antigen
  • hP
  • Antigen Species
  • Human
  • Peptide
  • MSLQRQFLR
  • Conjugate
  • PE
  • Application
  • FCM

Target

  • Antigen Introduction
  • In biochemistry, a hypothetical protein is a protein whose existence has been predicted, but for which there is a lack of experimental evidence that it is expressed in vivo. Sequencing of several genomes has resulted in numerous predicted open reading frames to which functions cannot be readily assigned. These proteins, either orphan or conserved hypothetical proteins, make up ~ 20% to 40% of proteins encoded in each newly sequenced genome. Even when there is enough evidence that the product of the gene is expressed, by techniques such as microarray and mass-spectrometry, it is difficult to assign a function to it given its lack of identity to protein sequences with annotated biochemical function. Nowadays, most protein sequences are inferred from computational analysis of genomic DNA sequence. Hypothetical proteins are created by gene prediction software during genome analysis. When the bioinformatic tool used for the gene identification finds a large open reading frame without a characterised homologue in the protein database, it returns "hypothetical protein" as an annotation remark.
  • Alternative Names
  • hP; hypothetical protein

Downloads

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Fab Fragment Antibody

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For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.

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