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PE-B*57:01/Human HSPA8 (KMKEIAEAY) MHC Tetramer (CAT#: MHC-LC4318)

This product is a tetramer of biotinylated peptide/MHC complex with streptavidin mainly composed of human HSPA8 of peptide KMKEIAEAY covering 67-75 and B*57:01 molecule. The pMHC tetramer recognizes CD8 T cells, and can be used in the analysis of individual antigen-specific T cells.


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Specific Inquiry
  • Size:
  • Gene Expression
  • Datasheet
  • MSDS
  • COA
Subcellular Location
Figure 1 IF staining of human cell line CACO-2
Figure 1 IF staining of human cell line CACO-2
(Immunofluorescent staining of human cell line CACO-2 shows localization to vesicles.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/52504/1028_G12_5_selected.jpg
Figure 2 IHC staining of human testis
Figure 2 IHC staining of human testis
(Immunohistochemical staining of human testis shows strong cytoplasmic and nuclear positivity in subset of cells in seminiferus ducts.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/52504/ihc_selected.jpg
Figure 3 IHC staining of human stomach
Figure 3 IHC staining of human stomach
(Immunohistochemical staining of human stomach shows strong cytoplasmic and nuclear positivity in glandular cells.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/2056/ihc_selected.jpg
Figure 4 IF staining of human cell line PC-3
Figure 4 IF staining of human cell line PC-3
(Immunofluorescent staining of human cell line PC-3 shows localization to vesicles.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/52504/987_G4_1_blue_red_green.jpg
Figure 5 IF staining of human cell line U-2 OS
Figure 5 IF staining of human cell line U-2 OS
(Immunofluorescent staining of human cell line U-2 OS shows localization to vesicles.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/52504/802_G12_2_blue_red_green.jpg
Normal Tissue
Figure 6 Liver
Figure 6 Liver
(Hepatocytes
Staining: Medium
Intensity: Moderate
Quantity: 75%-25%
Location: Nuclear)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/2056/5749_A_8_4.jpg
Figure 7 Lymph node
Figure 7 Lymph node
(Non-germinal center cells
Staining: Medium
Intensity: Moderate
Quantity:>75%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/2056/5749_A_7_8.jpg
RNA Expression
Figure 8 RNA cell line category: Low cell line specificity
Figure 8 RNA cell line category: Low cell line specificity
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000109971-HSPA8
Figure 8 RNA cell line category: Low cell line specificity
Figure 8 RNA cell line category: Low cell line specificity
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000109971-HSPA8

Specifications

  • Allele
  • B*57:01
  • Class
  • Class I
  • Antigen
  • HSPA8
  • Antigen Species
  • Human
  • Peptide
  • KMKEIAEAY
  • Range
  • 67-75
  • Conjugate
  • PE
  • Application
  • FCM

Target

  • Antigen Introduction
  • This gene encodes a member of the heat shock protein 70 family, which contains both heat-inducible and constitutively expressed members. This protein belongs to the latter group, which are also referred to as heat-shock cognate proteins. It functions as a chaperone, and binds to nascent polypeptides to facilitate correct folding. It also functions as an ATPase in the disassembly of clathrin-coated vesicles during transport of membrane components through the cell. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
  • Alternative Names
  • HSPA8; heat shock protein family A (Hsp70) member 8; LAP1; HSC54; HSC70; HSC71; HSP71; HSP73; LAP-1; NIP71; HEL-33; HSPA10; HEL-S-72p

Downloads

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MHC Tetramer for Cancer

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Recombinant Antibody

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MRO-0768-CN Rabbit Anti-HSPA8 Recombinant Antibody (clone CBACN-284) WB, IF, IHC, IP Rabbit IgG
MRO-1941-CN Rabbit Anti-HSPA8 Polyclonal Antibody (MRO-1941-CN) WB, IF, IHC, FC Rabbit IgG
VS3-WK1382 Mouse Anti-HSPA8 Recombinant Antibody (VS3-WK1382) WB, IHC-P Mouse IgG
VS4-WK233 Mouse Anti-HSPA8 Recombinant Antibody (VS4-WK233) ELISA, WB Mouse IgG
VS3-FY710 Recombinant Rabbit Anti-HSPA8 Antibody (clone R07-1B7) WB, IHC-P, IP Rabbit IgG

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For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.

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