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PE-DRB1*04:01/Human HLA-DRB1 (VYPEVTVYPAKT) MHC Tetramer (CAT#: MHC-LC3346)

This product is a tetramer of biotinylated peptide/MHC complex with streptavidin mainly composed of human HLA-DRB1 of peptide VYPEVTVYPAKT covering 124-135 and DRB1*04:01 molecule. The pMHC tetramer recognizes CD4 T cells, and can be used in the analysis of individual antigen-specific T cells.


See more MHC Tetramer products for HLA-DRB1
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  • Gene Expression
  • Datasheet
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Normal Tissue
Figure 1 Lymph node
Figure 1 Lymph node
(Germinal center cells
Staining: Medium
Intensity: Strong
Quantity: <25%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/15400/34565_A_8_8.jpg
Figure 2 Tonsil
Figure 2 Tonsil
(Germinal center cells
Staining: High
Intensity: Strong
Quantity: 75%-25%
Location: Cytoplasmic/membranous
Non-germinal center cells
Staining: Medium
Intensity: Strong
Quantity: <25%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/15400/34565_A_4_8.jpg
RNA Expression
Figure 3 RNA cell line category: Cell line enhanced (HDLM-2, HMC-1, THP-1, U-266/70, U-698, U-87 MG)
Figure 3 RNA cell line category: Cell line enhanced (HDLM-2, HMC-1, THP-1, U-266/70, U-698, U-87 MG)
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000196126-HLA-DRB1
Figure 3 RNA cell line category: Cell line enhanced (HDLM-2, HMC-1, THP-1, U-266/70, U-698, U-87 MG)
Figure 3 RNA cell line category: Cell line enhanced (HDLM-2, HMC-1, THP-1, U-266/70, U-698, U-87 MG)
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000196126-HLA-DRB1

Specifications

  • Allele
  • DRB1*04:01
  • Class
  • Class II
  • Antigen
  • HLA-DRB1
  • Antigen Species
  • Human
  • Peptide
  • VYPEVTVYPAKT
  • Range
  • 124-135
  • Conjugate
  • PE
  • Application
  • FCM

Target

  • Antigen Introduction
  • HLA class II histocompatibility antigen, DRB1 beta chain is a protein that in humans is encoded by the HLA-DRB1 gene. DRB1 encodes the most prevalent beta subunit of HLA-DR. Several alleles of DRB1 (shared epitope alleles) are associated with an increased incidence of rheumatoid arthritis.
  • Alternative Names
  • HLA-DRB1; HLA class II histocompatibility antigen, DRB1-4 beta chain precursor

Downloads

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See other products for "HLA-DRB1"

Fab Fragment Antibody

CAT Product Name Application Type
MOB-1090z-F(E) Recombinant Anti-Human HLA-DRB1 Antibody Fab Fragment Neut, IF, FuncS Fab
HPAB-0023-YC-F(E) Human Anti-HLA-DRB1 Recombinant Antibody (clone huA33); Fab Fragment ELISA Humanized Fab
HPAB-0024-YC-F(E) Human Anti-HLA-DRB1 Recombinant Antibody (clone de-immunized huA33); Fab Fragment ELISA Humanized Fab
HPAB-0025-YC-F(E) Human Anti-HLA-DRB1 Recombinant Antibody (clone HD4); Fab Fragment Cyt, WB Human Fab
HPAB-0026-YC-F(E) Human Anti-HLA-DRB1 Recombinant Antibody (clone HD8); Fab Fragment Cyt, WB Human Fab

scFv Fragment Antibody

CAT Product Name Application Type
MOB-1090z-S(P) Recombinant Anti-Human HLA-DRB1 Antibody scFv Fragment WB, FC, FuncS scFv
HPAB-0023-YC-S(P) Human Anti-HLA-DRB1 Recombinant Antibody (clone huA33); scFv Fragment ELISA Humanized scFv
HPAB-0024-YC-S(P) Human Anti-HLA-DRB1 Recombinant Antibody (clone de-immunized huA33); scFv Fragment ELISA Humanized scFv
HPAB-0025-YC-S(P) Human Anti-HLA-DRB1 Recombinant Antibody (clone HD4); scFv Fragment Cyt, WB Human scFv
HPAB-0026-YC-S(P) Human Anti-HLA-DRB1 Recombinant Antibody (clone HD8); scFv Fragment Cyt, WB Human scFv

Humanized Antibody

CAT Product Name Application Type
TAB-150 Anti-Human HLA DR beta Recombinant Antibody (Apolizumab) ELISA, IP, FC, FuncS, Neut, IF, ICC IgG1

Recombinant Antibody

CAT Product Name Application Type
MOB-0940CT Recombinant Mouse anti-Human HLA-DRB1 Monoclonal antibody (5j245) Cyt, FuncS
HPAB-0023-YC Human Anti-HLA-DRB1 Recombinant Antibody (clone huA33) ELISA Humanized IgG
HPAB-0024-YC Human Anti-HLA-DRB1 Recombinant Antibody (clone de-immunized huA33) ELISA Humanized IgG
VS3-FY681 Recombinant Mouse Anti-HLA-DRB1 Antibody (clone 5B3D2) ELISA, IHC, FC Mouse IgG1
VS3-FY682 Recombinant Mouse Anti-HLA-DRB1 Antibody (clone 5B3G1) ELISA, WB, IHC, FC Mouse IgG1

Rabbit Monoclonal Antibody

CAT Product Name Application Type
MOR-1623 Rabbit Anti-HLA-DRB1 Recombinant Antibody (clone DS1623AB) WB, IHC, ICC Rabbit IgG

ADCC Enhanced Antibody

CAT Product Name Application Type
AFC-TAB-150 Afuco™ Anti-HLA-DRB1 ADCC Recombinant Antibody (Apolizumab), ADCC Enhanced ELISA, IP, FC, FuncS, Neut, IF ADCC enhanced antibody

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