Anti-ROR1 (R11) scFv-Fc-Sec ADC (CAT#: ADC-155LCT)

This ADC product is composed of an anti-ROR1 scFv (clone R11) conjuagated via a engineered selenocysteine (Sec) residue linker to (R11-scFv-Fc-Sec).


Specific Inquiry
  • Gene Expression
  • Datasheet
  • MSDS
  • COA
RNA Expression

Specifications

  • Antibody Overview
  • Mouse Anti-Human Monoclonal (R11) Antibody, scFv-FC
  • Clone
  • anti-ROR1 scFv-Fc, R11
  • Linker
  • engineered selenocysteine (Sec) residue

Target

  • Introduction
  • This gene encodes a receptor tyrosine kinase-like orphan receptor that modulates neurite growth in the central nervous system. The encoded protein is a glycosylated type I membrane protein that belongs to the ROR subfamily of cell surface receptors. It is a pseudokinase that lacks catalytic activity and may interact with the non-canonical Wnt signalling pathway. This gene is highly expressed during early embryonic development but expressed at very low levels in adult tissues. Increased expression of this gene is associated with B-cell chronic lymphocytic leukaemia. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jun 2012]
  • Alternative Names
  • ROR1; receptor tyrosine kinase-like orphan receptor 1; NTRKR1; dJ537F10.1; tyrosine-protein kinase transmembrane receptor ROR1; neurotrophic tyrosine kinase, receptor-related 1;

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For Research Use Only. Not For Clinical Use.

For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.

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