Products

Recombinant Anti-CD19 Antibody (Fc glycosylation/Low fucosylated) (Gly-061LC-1)

This product is a chimeric (mouse/human) monoclonal antibody with N-glycosylation site in the Fc region. The antibody chR005-1 F20 with enhanced ADCC specifically binds human CD19 and can be potentially used in the treatment of B-cell malignancy.      

Glyco-engineering
Classification
Fc glycosylation/Low fucosylated
Glycosylation site
Asn297 in Fc region
Glycoform (ratio)
GN-GN-M-(M-GN)2
Glycosylation Type
N-glycosylation
Activity
Enhanced ADCC
Specifications
Target
CD19 (Cluster of differentiation-19)
Host Animal
Human
Derivation
Chimeric (mouse/human)
Type
Chimeric antibody (mouse/human)
Specificity
Human
Antibody Isotype
IgG1
Clone
chR005-1 F20
Applications
ELISA, FC
Target
Alternative Names
CD19; CD19 molecule; B4; CVID3; B-lymphocyte antigen CD19; differentiation antigen CD19; T-cell surface antigen Leu-12; B-lymphocyte surface antigen B4
Related Disease
B-cell malignancy
Entrez Gene ID
930
UniProt ID
P15391

For lab research use only, not for diagnostic, therapeutic or any in vivo human use.

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