Products

Recombinant Anti-CD19 Antibody (Fc glycosylation/Non fucosylated) (Gly-141LC-1)

This product is a non-fucosylated humanized monoclonal antibody. The antibody 3649-aFuc with enhanced ADCC specficfically binds to human CD19 and can be potentially used in the treatment of graft-versus-host disease and post-transplantation lymphoproliferative disorder.      

Glyco-engineering
Classification
Fc glycosylation/Non fucosylated
Glycosylation site
Asn297 in Fc region
Glycosylation Type
N-glycosylation
Activity
Enhanced ADCC
Specifications
Target
CD19 (Cluster of differentiation-19)
Host Animal
Human
Type
Humanized antibody
Specificity
Human
Antibody Isotype
IgG
Clone
3649-aFuc
Applications
ELISA
Target
Alternative Names
CD19; CD19 molecule; B4; CVID3; B-lymphocyte antigen CD19; differentiation antigen CD19; T-cell surface antigen Leu-12; B-lymphocyte surface antigen B4
Related Disease
Graft-versus-host disease and post-transplantation lymphoproliferative disorder
Entrez Gene ID
930
UniProt ID
P15391

For lab research use only, not for diagnostic, therapeutic or any in vivo human use.

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