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Recombinant Anti-Human CTGF Antibody (Fc glycosylation) (CAT#: Gly-119LC)

This product is a human monoclonal antibody with glycoyslation site at in Fc region. The antibody mAb1 with enhanced ADCC specficfically binds to human CTGF and can be potentially used in the treatment of cardiovascular disease.


See more Glyco-Engineering Antibody products for CTGF
Specific Inquiry
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  • Conjugation:
  • Endotoxin:
  • Purity:
  • Gene Expression
  • Datasheet
  • MSDS
  • COA
Subcellular Location
Figure 1 IF staining of human cell line U-2 OS
Figure 1 IF staining of human cell line U-2 OS
(Immunofluorescent staining of human cell line U-2 OS shows localization to the Golgi apparatus & vesicles.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/31074/564_D9_2_selected.jpg
Normal Tissue
Figure 2 IHC staining of human stomach, upper
Figure 2 IHC staining of human stomach, upper
(Immunohistochemical staining of human stomach, upper shows moderate positivity in plasma and stromal cells.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/31075/ihc_selected.jpg
Figure 3 Lymph node
Figure 3 Lymph node
(Non-germinal center cells Staining: High Intensity: Strong Quantity: 75%-25% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/5123/15554_A_9_8.jpg
Figure 4 Cerebral cortex
Figure 4 Cerebral cortex
(Neuronal cells Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/5123/15554_B_7_5.jpg
Figure 5 Liver
Figure 5 Liver
(Hepatocytes Staining: Medium Intensity: Moderate Quantity: 75%-25% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/5123/15554_A_8_4.jpg
Figure 6 Smooth muscle
Figure 6 Smooth muscle
(Smooth muscle cells Staining: High Intensity: Strong Quantity:>75% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/5123/15554_B_5_7.jpg
RNA Expression
Figure 7 RNA cell line category: Cell line enhanced (EFO-21, HUVEC TERT2, TIME)
Figure 7 RNA cell line category: Cell line enhanced (EFO-21, HUVEC TERT2, TIME)
(Cell lines ordered by descending RNA expression order)
* Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000118523-CTGF

Glyco-engineering

  • Glycosylation site
  • Fc region
  • Glycosylation Type
  • N-glycosylation
  • Activity
  • Enhanced ADCC

Specifications

  • Target
  • CTGF (Connective tissue growth factor)
  • Host Species
  • Human
  • Derivation
  • 8C12-F10 cell line
  • Type
  • Human antibody
  • Specificity
  • Human
  • Clone
  • mAb1
  • Applications
  • ELISA

Target

  • Alternative Names
  • CTGF; connective tissue growth factor; CCN2; NOV2; HCS24; IGFBP8; IBP-8; IGFBP-8; CCN family member 2; IGF-binding protein 8; hypertrophic chondrocyte-specific protein 24; insulin-like growth factor-binding protein 8
  • Related Disease
  • Cardiovascular disease

Downloads

Download resources about recombinant antibody development and antibody engineering to boost your research.

See other products for "CTGF"

Recombinant Antibody

CAT Product Name Application Type
MOB-1576z Mouse Anti-CTGF Recombinant Antibody (clone 32G9) ELISA, IHC Mouse IgG1
HPAB-0181-YC Human Anti-CTGF Recombinant Antibody (HPAB-0181-YC) ELISA, FuncS Human IgG
MRO-1793-CN Rabbit Anti-CTGF Polyclonal Antibody (MRO-1793-CN) WB, IF, IHC Rabbit IgG

Mouse Antibody

CAT Product Name Application Type
TAB-080MZ Mouse Anti-CTGF Recombinant Antibody (TAB-080MZ) ELISA Mouse IgG
TAB-080MZ-S(P) Mouse Anti-CTGF Recombinant Antibody; scFv Fragment (TAB-080MZ-S(P)) ELISA Mouse scFv
TAB-080MZ-F(E) Mouse Anti-CTGF Recombinant Antibody; Fab Fragment (TAB-080MZ-F(E)) ELISA Mouse Fab

Human Antibody

CAT Product Name Application Type
TAB-081MZ Human Anti-CTGF Recombinant Antibody (TAB-081MZ) ELISA Human IgG
TAB-082MZ Human Anti-CTGF Recombinant Antibody (TAB-082MZ) ELISA Human IgG
TAB-081MZ-S(P) Human Anti-CTGF Recombinant Antibody; scFv Fragment (TAB-081MZ-S(P)) ELISA Human scFv
TAB-082MZ-S(P) Human Anti-CTGF Recombinant Antibody; scFv Fragment (TAB-082MZ-S(P)) ELISA Human scFv
TAB-443CQ Anti-Human CTGF Recombinant Antibody (Pamrevlumab) ELISA, IHC, FC, IP, IF, Inhib IgG1, κ

scFv Fragment Antibody

CAT Product Name Application Type
HPAB-0181-YC-S(P) Human Anti-CTGF Recombinant Antibody; scFv Fragment (HPAB-0181-YC-S(P)) ELISA, FuncS Human scFv

Fab Fragment Antibody

CAT Product Name Application Type
HPAB-0181-YC-F(E) Human Anti-CTGF Recombinant Antibody; Fab Fragment (HPAB-0181-YC-F(E)) ELISA, FuncS Human Fab

ADCC Enhanced Antibody

CAT Product Name Application Type
AFC-TAB-443CQ Afuco™ Anti-CTGF ADCC Recombinant Antibody (Pamrevlumab), ADCC Enhanced ELISA, IHC, FC, IP, IF, Inhib ADCC enhanced antibody

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For Research Use Only. Not For Clinical Use.

For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.

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