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Recombinant Anti-ERBB2 Antibody (Fc glycosylation/Low fucosylated) (Gly-140LC-1)

This product is a low-fucosylated humanized monoclonal antibody. The anibody Fuc-trastuzumab with enhanced ADCC specficfically binds to human HER-2 and can be potentially used in the treatment of breast cancer.      

Glyco-engineering
Classification
Fc glycosylation/Low fucosylated
Glycosylation site
Asn297 in Fc region
Glycosylation Type
N-glycosylation
Activity
Enhanced ADCC
Specifications
Target
HER-2 (Human epidermal growth factor receptor 2)
Host Animal
Human
Type
Humanized antibody
Specificity
Human
Antibody Isotype
IgG
Clone
Fuc-trastuzumab
Applications
ELISA
Target
Alternative Names
ERBB2; erb-b2 receptor tyrosine kinase 2; NEU; NGL; HER2; TKR1; CD340; HER-2
Related Disease
Breast cancer
Entrez Gene ID
2064
UniProt ID
P04626

For lab research use only, not for diagnostic, therapeutic or any in vivo human use.

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