Recombinant Anti-Human FCER2 Antibody (Fc glycosylation/Non fucosylated) (CAT#: Gly-157LC)
This product is a non-fucosylated chimeric (primate/human) monoclonal antibody. The antibody with enhanced ADCC specficfically binds to human CD23 and can be potentially used in the treatment of chronic lymphocytic leukemia.
Specific Inquiry
Normal Tissue
RNA Expression
Figure 1 High expression in lymph node
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/8928/24032_A_9_8_val_selected.jpg
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/8928/24032_A_9_8_val_selected.jpg
Figure 2 Low expression in endometrium 1
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/8928/24032_B_4_3_val_selected.jpg
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/8928/24032_B_4_3_val_selected.jpg
Figure 3 Bone marrow
(Hematopoietic cells Staining: Medium Intensity: Strong Quantity: <25% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/2624/6435_B_5_4.jpg
(Hematopoietic cells Staining: Medium Intensity: Strong Quantity: <25% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/2624/6435_B_5_4.jpg
Figure 4 Lymph node
(Germinal center cells Staining: High Intensity: Strong Quantity: 75%-25% Location: Cytoplasmic/ membranous Non-germinal center cells Staining: Medium Intensity: Strong Quantity: <25% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/2624/6435_A_9_8.jpg
(Germinal center cells Staining: High Intensity: Strong Quantity: 75%-25% Location: Cytoplasmic/ membranous Non-germinal center cells Staining: Medium Intensity: Strong Quantity: <25% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/2624/6435_A_9_8.jpg
Figure 5 RNA cell line category: Cell line enriched (HDLM-2)
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000104921-FCER2
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000104921-FCER2
Glyco-engineering
- Glycosylation site
- Fc region
- Glycosylation Type
- N-glycosylation
- Activity
- Enhanced ADCC
Specifications
- Target
- CD23 (Cluster of differentiation-23)
- Host Species
- Human
- Derivation
- Chimeric (primate/human)
- Type
- Chimeric antibody (primate/human)
- Specificity
- Human
- Applications
- ELISA
Target
- Alternative Names
- FCER2; Fc fragment of IgE receptor II; CD23; FCE2; CD23A; IGEBF; CLEC4J; BLAST-2
- Related Disease
- Chronic lymphocytic leukemia
- Gene ID
- 2208
- UniProt ID
- P06734
Downloads
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Chimeric Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-231 | Anti-Human CD23 Recombinant Antibody (Gomiliximab) | WB, Neut, ELISA, IF, IP, FuncS, FC | IgG1 - kappa |
Low- or Non-fucosylated Oligosaccharide
| CAT | Product Name | Application | Type |
|---|---|---|---|
| Gly-157LC-1 | Recombinant Anti-Human FCER2 Antibody (Fc glycosylation/Non fucosylated) | ELISA | Chimeric antibody (primate/human) |
Neutralizing Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| NEUT-786CQ | Mouse Anti-FCER2 Recombinant Antibody (clone CBL016) | Neut, FC, WB | Mouse IgG2 |
| NEUT-788CQ | Mouse Anti-FCER2 Recombinant Antibody (clone MM0164-2C23) | WB, Neut, FC | Mouse IgG1 |
Blocking Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| NEUT-787CQ | Mouse Anti-FCER2 Recombinant Antibody (clone TU1) | FC, IHC-Fr, ICC, WB, Block | Mouse IgG3, κ |
| NEUT-789CQ | Mouse Anti-FCER2 Recombinant Antibody (clone CBL329) | ELISA, WB, Block, CyTOF®, FC | Mouse IgG1 |
Rabbit Monoclonal Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOR-1268 | Hi-Affi™ Rabbit Anti-FCER2 Recombinant Antibody (clone DS1268AB) | IHC | Rabbit IgG |
MHC Tetramer for Cancer
ADCC Enhanced Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| AFC-TAB-231 | Afuco™ Anti-FCER2 ADCC Recombinant Antibody (Gomiliximab), ADCC Enhanced | Neut, ELISA, IF, IP, FuncS | ADCC enhanced antibody |
scFv Fragment Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-1148-FY-F(E) | Human Anti-FCER2 Recombinant Antibody; Fab Fragment (HPAB-1148-FY-F(E)) | Activ | Human Fab |
| HPAB-1149-FY-F(E) | Monkey Anti-FCER2 Recombinant Antibody; Fab Fragment (HPAB-1149-FY-F(E)) | Activ | Monkey Fab |
| HPAB-0530-YJ-S(P) | Mouse Anti-FCER2 Recombinant Antibody (clone 1E9); scFv Fragment | ELISA, IHC | Mouse scFv |
| HPAB-0531-YJ-S(P) | Human Anti-FCER2 Recombinant Antibody (clone ch1E9); scFv Fragment | ELISA, IHC | Human scFv |
Fab Fragment Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-1148-FY-S(P) | Monkey Anti-FCER2 Recombinant Antibody; scFv Fragment (HPAB-1148-FY-S(P)) | Activ | Monkey scFv |
| HPAB-1149-FY-S(P) | Monkey Anti-FCER2 Recombinant Antibody; scFv Fragment (HPAB-1149-FY-S(P)) | Activ | Monkey scFv |
| HPAB-0530-YJ-F(E) | Mouse Anti-FCER2 Recombinant Antibody (clone 1E9); Fab Fragment | ELISA, IHC | Mouse Fab |
| HPAB-0531-YJ-F(E) | Human Anti-FCER2 Recombinant Antibody (clone ch1E9); Fab Fragment | ELISA, IHC | Chimeric (mouse/human) Fab |
Recombinant Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-0530-YJ | Mouse Anti-FCER2 Recombinant Antibody (clone 1E9) | ELISA, IHC | Mouse IgG1 |
| HPAB-0531-YJ | Human Anti-FCER2 Recombinant Antibody (clone ch1E9) | ELISA, IHC | Chimeric (mouse/human) IgG1 |
| VS3-XY675 | Mouse Anti-FCER2 Recombinant Antibody, FITC (clone 4AEBVCS2) | FC, IF | Mouse IgG1 |
| VS3-XY676 | Mouse Anti-FCER2 Recombinant Antibody (clone 4AEBVCS2) | FC, IF | Mouse IgG1 |
| VS3-XY679 | Mouse Anti-FCER2 Recombinant Antibody (clone 5B5) | ELISA, FC | Mouse IgG1 |
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For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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