Recombinant Anti-Human FOLR1 Antibody (Fc glycosylation/Non fucosylated) (CAT#: Gly-029LC)
This product is a human monoclonal antibody with N-glycosylation site Asn299 in the heavy chain. Antibody MORAb-003 has increased ADCC, it specifically binds human FRA and can be potentially used in the treatment of FRA-mediated disease such as cancer.
Specific Inquiry
Subcellular Location
RNA Expression
Figure 1 IF staining of human cell line HeLa
(Immunofluorescent staining of human cell line HeLa shows localization to nuclear membrane.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/77030/1659_B3_2_selected.jpg
(Immunofluorescent staining of human cell line HeLa shows localization to nuclear membrane.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/77030/1659_B3_2_selected.jpg
Figure 2 RNA cell line category: Group enriched (HeLa, RPTEC TERT1)
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000110195-FOLR1
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000110195-FOLR1
Figure 2 RNA cell line category: Group enriched (HeLa, RPTEC TERT1)
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000110195-FOLR1
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000110195-FOLR1
Glyco-engineering
- Glycosylation site
- Asn299 of heavy chain
- Glycoform (ratio)
- NGA2
- Glycosylation Type
- N-glycosylation
- Activity
- Increased ADCC
Specifications
- Target
- FOLR1 (Folate receptor alpha)
- Host Species
- Human
- Type
- Human antibody
- Specificity
- Human
- Clone
- MORAb-003
- Expression Host
- CHO-K1
- Applications
- ELISA
Target
- Alternative Names
- FOLR1; folate receptor 1 (adult); FBP; FOLR; folate receptor alpha; FR-alpha; KB cells FBP; folate binding protein; folate receptor, adult; adult folate-binding protein; ovarian tumor-associated antigen MOv18;
- Related Disease
- FRA-mediated disease
- Gene ID
- 2348
- UniProt ID
- A0A024R5H1
Downloads
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Intrabody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| IAB-B029(A) | Recombinant Anti-human FOLR1 Intrabody [(D-Arg)9] | PCA, Neut, FuncS | scFv-(D-Arg)9 |
| IAB-B029(G) | Recombinant Anti-human FOLR1 Intrabody [+36 GFP] | WB, Neut, FuncS | scFv-(+36GFP) |
| IAB-B029(T) | Recombinant Anti-human FOLR1 Intrabody [Tat] | WB, ICC, Neut, FuncS | scFv-Tat |
Humanized Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-113 | Anti-Human folate receptor 1 Recombinant Antibody (Farletuzumab) | FC, IP, ELISA, Neut, FuncS, IF, ICC | IgG1 - kappa |
| TAB-019CQ | Human Anti-FOLR1 Recombinant Antibody (TAB-019CQ) | ELISA, WB, IHC | Human IgG1, κ |
| TAB-019CQ-S(P) | Human Anti-FOLR1 Recombinant Antibody; scFv Fragment (TAB-019CQ-S(P)) | ELISA, WB, IHC | Human scFv |
| TAB-019CQ-F(E) | Human Anti-FOLR1 Recombinant Antibody; Fab Fragment (TAB-019CQ-F(E)) | ELISA, WB, IHC | Humanized Fab |
Human Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-016CQ | Human Anti-FOLR1 Recombinant Antibody (TAB-016CQ) | ELISA, FC, WB | Human IgG |
| TAB-016CQ-S(P) | Human Anti-FOLR1 Recombinant Antibody; scFv Fragment (TAB-016CQ-S(P)) | ELISA, FC, WB | Human scFv |
| TAB-016CQ-F(E) | Human Anti-FOLR1 Recombinant Antibody; Fab Fragment (TAB-016CQ-F(E)) | ELISA, FC, WB | Human Fab |
| TAB-382CQ-S(P) | Anti-Human FOLR1 Recombinant Antibody scFv Fragment (KHK2805) | IHC | Human antibody |
| TAB-382CQ-F(E) | Anti-Human FOLR1 Recombinant Antibody Fab Fragment (KHK2805) | IHC | Human antibody |
Mouse Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-017CQ | Rat Anti-FOLR1 Recombinant Antibody (TAB-017CQ) | ELISA, WB, IHC | Rat IgG1, κ |
| TAB-020CQ | Mouse Anti-FOLR1 Recombinant Antibody (TAB-020CQ) | ELISA, FC, WB, IHC | Mouse IgG1 |
| TAB-017CQ-S(P) | Rat Anti-FOLR1 Recombinant Antibody; scFv Fragment (TAB-017CQ-S(P)) | ELISA, WB, IHC | Rat scFv |
| TAB-020CQ-S(P) | Mouse Anti-FOLR1 Recombinant Antibody; scFv Fragment (TAB-020CQ-S(P)) | ELISA, FC, WB, IHC | Mouse scFv |
| TAB-017CQ-F(E) | Rat Anti-FOLR1 Recombinant Antibody; Fab Fragment (TAB-017CQ-F(E)) | ELISA, WB, IHC | Rat Fab |
Chimeric Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-018CQ | Human Anti-FOLR1 Recombinant Antibody (TAB-018CQ) | ELISA, WB, IHC | Chimeric (Rat/Human) IgG1, κ |
| TAB-018CQ-S(P) | Human Anti-FOLR1 Recombinant Antibody; scFv Fragment (TAB-018CQ-S(P)) | ELISA, WB, IHC | Human scFv |
| TAB-018CQ-F(E) | Human Anti-FOLR1 Recombinant Antibody; Fab Fragment (TAB-018CQ-F(E)) | ELISA, WB, IHC | Chimeric (Rat/Human) Fab |
Low- or Non-fucosylated Oligosaccharide
| CAT | Product Name | Application | Type |
|---|---|---|---|
| Gly-029LC-1 | Recombinant Anti-Human FOLR1 Antibody (Fc glycosylation/Non fucosylated) | ELISA | Human antibody |
Fc Glycosylation
| CAT | Product Name | Application | Type |
|---|---|---|---|
| Gly-030LC | Recombinant Anti-Human FOLR1 Antibody (Fc glycosylation) | ELISA | Human antibody |
| Gly-116LC | Recombinant Anti-Human FOLR1 Antibody (Fc glycosylation) | ELISA | Human antibody |
Rabbit Monoclonal Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOR-1333 | Hi-Affi™ Rabbit Anti-FOLR1 Recombinant Antibody (clone DS1333AB) | WB | Rabbit IgG |
Recombinant Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-0115-CN | Mouse Anti-FOLR1 Recombinant Antibody (HPAB-0115-CN) | ELISA, FC, IHC | Mouse IgG2b |
| HPAB-0116-CN | Human Anti-FOLR1 Recombinant Antibody (HPAB-0116-CN) | ELISA, FC, IHC | Humanized IgG1 |
| HPAB-0117-CN | Mouse Anti-FOLR1 Recombinant Antibody (HPAB-0117-CN) | ELISA, FC | Mouse IgG |
| HPAB-0118-CN | Mouse Anti-FOLR1 Recombinant Antibody (HPAB-0118-CN) | ELISA, FC | Mouse IgG |
| HPAB-0119-CN | Mouse Anti-FOLR1 Recombinant Antibody (HPAB-0119-CN) | ELISA, FC, IHC, WB | Mouse IgG1, κ |
Fab Fragment Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-0115-CN-F(E) | Mouse Anti-FOLR1 Recombinant Antibody; Fab Fragment (HPAB-0115-CN-F(E)) | ELISA, FC, IHC | Mouse Fab |
| HPAB-0116-CN-F(E) | Human Anti-FOLR1 Recombinant Antibody; Fab Fragment (HPAB-0116-CN-F(E)) | ELISA, FC, IHC | Humanized Fab |
| HPAB-0117-CN-F(E) | Mouse Anti-FOLR1 Recombinant Antibody; Fab Fragment (HPAB-0117-CN-F(E)) | ELISA, FC | Mouse Fab |
| HPAB-0118-CN-F(E) | Mouse Anti-FOLR1 Recombinant Antibody; Fab Fragment (HPAB-0118-CN-F(E)) | ELISA, FC | Mouse Fab |
| HPAB-0080-FY-F(E) | Human Anti-FOLR1 Recombinant Antibody; Fab Fragment (HPAB-0080-FY-F(E)) | FC | Humanized Fab |
scFv Fragment Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-0080-FY-S(P) | Human Anti-FOLR1 Recombinant Antibody; scFv Fragment (HPAB-0080-FY-S(P)) | FC | Human scFv |
| HPAB-0312-WJ-S(P) | Mouse Anti-FOLR1 Recombinant Antibody; scFv Fragment (HPAB-0312-WJ-S(P)) | ELISA, IHC, FC | Mouse scFv |
| HPAB-0313-WJ-S(P) | Mouse Anti-FOLR1 Recombinant Antibody; scFv Fragment (HPAB-0313-WJ-S(P)) | ELISA, IHC, FC | Mouse scFv |
| HPAB-0314-WJ-S(P) | Mouse Anti-FOLR1 Recombinant Antibody; scFv Fragment (HPAB-0314-WJ-S(P)) | ELISA, IHC, FC | Mouse scFv |
| HPAB-M0094-YC-S(P) | Human Anti-FOLR1 Recombinant Antibody; scFv Fragment (HPAB-M0094-YC-S(P)) | FuncS | Humanized scFv |
ADCC Enhanced Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| AFC-TAB-113 | Afuco™ Anti-FOLR1 ADCC Recombinant Antibody (Farletuzumab), ADCC Enhanced | FC, IP, ELISA, Neut, FuncS, IF | ADCC enhanced antibody |
MHC Tetramer for Cancer
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MHC-CN0049 | APC-A*02:01/Human FBP (EIWTHSYKV) MHC Tetramer | FCM | |
| MHC-CN0050 | PE-A*02:01/Human FBP (EIWTHSYKV) MHC Tetramer | FCM | |
| MHC-CN0685 | PE-A*02:01/Human FOLR1 (EIWTHSYKV) MHC Tetramer | FCM, IHC | |
| MHC-CN0686 | APC-A*02:01/Human FOLR1 (EIWTHSYKV) MHC Tetramer | FCM, IHC | |
| MHC-CN0687 | FITC-A*02:01/Human FOLR1 (EIWTHSYKV) MHC Tetramer | FCM, IHC |
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For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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