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Recombinant Anti-Human IL15 Antibody (Fc glycosylation/High-mannose glycosylated) (CAT#: Gly-198LC)

This product is a high-mannose glycosylatedd human monoclonal antibody. The antibody with enhanced ADCC specifically binds to human IL-15 and can be potentially used in the treatment of autoimmune disease.


See more Glyco-Engineering Antibody products for IL15
Specific Inquiry
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  • Conjugation:
  • Endotoxin:
  • Purity:
  • Gene Expression
  • Datasheet
  • MSDS
  • COA
Subcellular Location
Figure 1 IF staining of human cell line A549
Figure 1 IF staining of human cell line A549
(Immunofluorescent staining of human cell line A549 shows localization to nuclear speckles & cytosol.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/37738/if_selected.jpg
Figure 2 IHC staining of human lymph node
Figure 2 IHC staining of human lymph node
(Immunohistochemical staining of human lymph node shows strong cytoplasmic positivity in reaction center cells.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/4457/ihc_selected.jpg
Figure 3 IF staining of human cell line HeLa
Figure 3 IF staining of human cell line HeLa
(Immunofluorescent staining of human cell line HeLa shows localization to nuclear speckles & cytosol.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/37738/785_B10_1_red_green.jpg
Figure 4 IF staining of human cell line U-2 OS
Figure 4 IF staining of human cell line U-2 OS
(Immunofluorescent staining of human cell line U-2 OS shows localization to nuclear speckles & cytosol.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/37738/783_B10_1_red_green.jpg
Normal Tissue
Figure 5 Cerebral cortex
Figure 5 Cerebral cortex
(Neuronal cells
Staining: High
Intensity: Strong
Quantity:>75%
Location: Cytoplasmic/membranous nuclear)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/4457/15421_B_8_5.jpg
Figure 6 Lung
Figure 6 Lung
(Macrophages
Staining: Medium
Intensity: Moderate
Quantity:>75%
Location: Cytoplasmic/membranous nuclear)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/4457/15421_A_1_4.jpg
Figure 7 Colon
Figure 7 Colon
(Glandular cells
Staining: Medium
Intensity: Moderate
Quantity:>75%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/4457/15421_A_8_3.jpg
Figure 8 Testis
Figure 8 Testis
(Cells in seminiferous ducts
Staining: High
Intensity: Strong
Quantity:>75%
Location: Cytoplasmic/membranous nuclear
Leydig cells
Staining: Medium
Intensity: Moderate
Quantity:>75%
Location: Cytoplasmic/membranous nuclear)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/4457/15421_A_6_6.jpg
Figure 9 Lymph node
Figure 9 Lymph node
(Germinal center cells
Staining:

High

Intensity: Strong
Quantity:>75%
Location: Cytoplasmic/
membranous
nuclear
Non-germinal center cells
Staining:

High

Intensity: Strong
Quantity:>75%
Location: Cytoplasmic/
membranous
nuclear)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/4457/15421_A_9_8.jpg
RNA Expression
Figure 10 RNA cell line category: Cell line enhanced (HDLM-2, Karpas-707)
Figure 10 RNA cell line category: Cell line enhanced (HDLM-2, Karpas-707)
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000164136-IL15
Figure 10 RNA cell line category: Cell line enhanced (HDLM-2, Karpas-707)
Figure 10 RNA cell line category: Cell line enhanced (HDLM-2, Karpas-707)
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000164136-IL15

Glyco-engineering

  • Glycosylation site
  • Fc region
  • Glycoform (ratio)
  • Man5 GlcNAc2
  • Glycosylation Type
  • N-glycosylation
  • Activity
  • Enhanced ADCC

Specifications

  • Target
  • IL-15 (Interleukin 15)
  • Host Species
  • Human
  • Type
  • Human antibody
  • Specificity
  • Human
  • Applications
  • ELISA

Target

  • Alternative Names
  • IL15; interleukin 15; IL-15; interleukin-15
  • Related Disease
  • Autoimmune disease

Related Resources

  • Related Diseases
  • Related Signaling Pathways

Downloads

Download resources about recombinant antibody development and antibody engineering to boost your research.

See other products for "IL15"

Fab Fragment Antibody

CAT Product Name Application Type
MOB-1254z-F(E) Recombinant Anti-Human IL15 Antibody Fab Fragment IF, FACS, FuncS Fab
HPAB-S0072-YC-F(E) Human Anti-IL15 Recombinant Antibody (clone 4H10); Fab Fragment ELISA Human Fab
HPAB-S0073-YC-F(E) Human Anti-IL15 Recombinant Antibody (clone 1H3); Fab Fragment ELISA Human Fab
HPAB-S0074-YC-F(E) Human Anti-IL15 Recombinant Antibody (clone 3C1); Fab Fragment ELISA Human Fab
HPAB-S0075-YC-F(E) Human Anti-IL15 Recombinant Antibody (clone 8C5); Fab Fragment ELISA Human Fab

scFv Fragment Antibody

CAT Product Name Application Type
MOB-1254z-S(P) Recombinant Anti-Human IL15 Antibody scFv Fragment WB, IF, FuncS scFv
PSBZ-081 Human Anti-IL15 Recombinant Antibody (clone DISC0280); scFv Fragment Neut Human scFv
HPAB-0238-YC-S(P) Human Anti-IL15 Recombinant Antibody; scFv Fragment (HPAB-0238-YC-S(P)) ELISA, FC, FuncS Human scFv
HPAB-0359-WJ-S(P) Mouse Anti-IL15 Recombinant Antibody (clone IL15-3); scFv Fragment ELISA Mouse scFv
HPAB-S0075-YC-S(P) Human Anti-IL15 Recombinant Antibody (clone 8C5); scFv Fragment ELISA Human scFv

Rat Antibody

CAT Product Name Application Type
TAB-398CL Human Anti-IL15 Recombinant Antibody (TAB-398CL) ELISA, WB Human IgG

ADCC Enhanced Antibody

CAT Product Name Application Type
AFC-382CL Afuco™ Anti-IL15 Recombinant Antibody (AFC-382CL), ADCC Enhanced ELISA, WB Human IgG1

Humanized Antibody

CAT Product Name Application Type
TAB-0234CL Human Anti-IL15 Recombinant Antibody (TAB-0234CL) ELISA Human IgG
TAB-0235CL Human Anti-IL15 Recombinant Antibody (TAB-0235CL) ELISA Human IgG
TAB-0236CL Human Anti-IL15 Recombinant Antibody (TAB-0236CL) ELISA Human IgG
TAB-0237CL Human Anti-IL15 Recombinant Antibody (TAB-0237CL) ELISA Human IgG
TAB-0238CL Human Anti-IL15 Recombinant Antibody (TAB-0238CL) ELISA Human IgG

Human Antibody

CAT Product Name Application Type
TAB-075ZJ Anti-Human IL-15 Recombinant Antibody (DISC0100) ELISA Human antibody
TAB-076ZJ Anti-Human IL-15 Recombinant Antibody (DISC0280) ELISA Human antibody
TAB-075ZJ-S(P) Anti-Human IL-15 Recombinant Antibody scFv Fragment (DISC0100) ELISA Human antibody
TAB-075ZJ-F(E) Anti-Human IL-15 Recombinant Antibody Fab Fragment (DISC0100) ELISA Human antibody
TAB-076ZJ-F(E) Anti-Human IL-15 Recombinant Antibody Fab Fragment (DISC0280) ELISA Human antibody

High-mannose Glycoform

CAT Product Name Application Type
Gly-198LC-1 Recombinant Anti-Human IL15 Antibody (Fc glycosylation/High-mannose glycosylated) ELISA Human antibody

Blocking Antibody

CAT Product Name Application Type
NEUT-1194CQ Mouse Anti-IL15 Recombinant Antibody (clone B-E29) Block Mouse IgG1

Neutralizing Antibody

CAT Product Name Application Type
NEUT-1195CQ Mouse Anti-IL15 Recombinant Antibody (clone CBL096) Neut, WB Mouse IgG1
NEUT-1196CQ Mouse Anti-IL15 Recombinant Antibody (clone CBL457) WB, CyTOF, ICFC, Neut Mouse IgG1
NEUT-1197CQ Mouse Anti-IL15 Recombinant Antibody (clone CBL757) ELISA, Neut Mouse IgG1
NEUT-1198CQ Mouse Anti-IL15 Recombinant Antibody (clone CBL758) WB, Neut Mouse IgG1
NEUT-1199CQ Mouse Anti-IL15 Recombinant Antibody (clone ct2nu) FuncS, Neut Mouse IgG1, κ

Rabbit Monoclonal Antibody

CAT Product Name Application Type
MOR-1792 Rabbit Anti-IL15 Recombinant Antibody (clone DS1792AB) WB Rabbit IgG

Recombinant Antibody

CAT Product Name Application Type
HPAB-0359-WJ Mouse Anti-IL15 Recombinant Antibody (clone IL15-3) ELISA Mouse IgG
HPAB-S0072-YC Human Anti-IL15 Recombinant Antibody (clone 4H10) ELISA Human IgG
HPAB-S0073-YC Human Anti-IL15 Recombinant Antibody (clone 1H3) ELISA Human IgG
HPAB-S0074-YC Human Anti-IL15 Recombinant Antibody (clone 3C1) ELISA Human IgG
HPAB-S0075-YC Human Anti-IL15 Recombinant Antibody (clone 8C5) ELISA Human IgG

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For Research Use Only. Not For Clinical Use.

For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.

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