Recombinant Human Anti-human CDKN1A Antibody (CAT#: MHH-190)
Recombinant Human Antibody is capable of binding to Human CDKN1A, expressed in HEK 293 cells. Expressed as the combination of a heavy chain (HC) containing VH from anti-CDKN1A mAb and CH1-3 region of human IgG1 and a light chain (LC) encoding VL from anti-CDKN1A mAb and CL of human kappa light chain. Exists as a disulfide linked dimer of the HC and LC hetero-dimer under non-reducing condition.
Specific Inquiry
Subcellular Location
Normal Tissue
RNA Expression
Figure 1 IF staining of human cell line RT4
(Immunofluorescent staining of human cell line RT4 shows localization to nucleoplasm.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/5946/1541_C12_6_selected.jpg
(Immunofluorescent staining of human cell line RT4 shows localization to nucleoplasm.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/5946/1541_C12_6_selected.jpg
Figure 2 IHC staining of human cervix, uterine
(Immunohistochemical staining of human cervix, uterine shows nuclear positivity in squamous cells.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/64/156817_B_8_3_selected.jpg
(Immunohistochemical staining of human cervix, uterine shows nuclear positivity in squamous cells.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/64/156817_B_8_3_selected.jpg
Figure 3 IHC staining of human urinary bladder
(Immunohistochemical staining of human urinary bladder shows strong nuclear positivity in urothelial cells.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/69401/155899_A_6_5_selected.jpg
(Immunohistochemical staining of human urinary bladder shows strong nuclear positivity in urothelial cells.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/69401/155899_A_6_5_selected.jpg
Figure 4 Colon
(Glandular cells
Staining: Medium
Intensity: Strong
Quantity: <25%
Location: Nuclear)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/64/159107_A_7_3.jpg
(Glandular cells
Staining: Medium
Intensity: Strong
Quantity: <25%
Location: Nuclear)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/64/159107_A_7_3.jpg
Figure 5 Pancreas
(Pancreatic endocrine cells
Staining: Medium
Intensity: Moderate
Quantity: 75%-25%
Location: Nuclear)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/64/159107_A_1_3.jpg
(Pancreatic endocrine cells
Staining: Medium
Intensity: Moderate
Quantity: 75%-25%
Location: Nuclear)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/64/159107_A_1_3.jpg
Figure 6 Testis
(Leydig cells
Staining: High
Intensity: Strong
Quantity: 75%-25%
Location: Nuclear)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/64/159107_A_5_6.jpg
(Leydig cells
Staining: High
Intensity: Strong
Quantity: 75%-25%
Location: Nuclear)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/64/159107_A_5_6.jpg
Figure 7 RNA cell line category: Cell line enhanced (HHSteC, HSkMC, hTCEpi, LHCN-M2)
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000124762-CDKN1A
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000124762-CDKN1A
Specifications
- Immunogen
- Human cyclin-dependent kinase inhibitor 1A (p21, Cip1)
- Host Species
- Human
- Derivation
- Human
- Type
- IgG
- Specificity
- Tested positive against native Human cyclin-dependent kinase inhibitor 1A (p21, Cip1)
- Species Reactivity
- Human
- Applications
- Products can be used for: Enzyme-linked Immunosorbent Assay; Immunofluorescence; Functional Study
Product Property
- Purity
- 90–95% (SDS-PAGE)
- Storage
- Store at -20°C for long-term storage. Store at 4°C for up to one month. Avoid freeze/thaw cycles.
Target
- Alternative Names
- CDKN1A; cyclin-dependent kinase inhibitor 1A (p21, Cip1); P21; CIP1; SDI1; WAF1; CAP20; CDKN1; MDA-6; p21CIP1; cyclin-dependent kinase inhibitor 1; DNA synthesis inhibitor; CDK-interacting protein 1; CDK-interaction protein 1; wild-type p53-activated frag
- Gene ID
- 1026
- UniProt ID
- A0A024RCX5
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
Download resources about recombinant antibody development and antibody engineering to boost your research.
See other products for "CDKN1A"
Fab Fragment Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-190-F(E) | Recombinant Anti-human CDKN1A Antibody Fab Fragment | FC, Neut, Funcs | Fab |
| MHH-190-F(E) | Recombinant Human Anti-human CDKN1A Antibody Fab Fragment | RIA, IF, FuncS | Fab |
scFv Fragment Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-190-S(P) | Recombinant Anti-human CDKN1A Antibody scFv Fragment | IF, FC, Biosensors, FuncS | scFv |
| MHH-190-S(P) | Recombinant Human Anti-human CDKN1A Antibody scFv Fragment | WB, IF, FuncS | scFv |
Recombinant Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-2113MZ | Recombinant Mouse Anti-Human CDKN1A Antibody (clone FB20) | FC, ICC, IHC-Fr, IHC-P, IP, WB | Mouse antibody |
| ZG-0797F | Mouse Anti-CDKN1A Recombinant Antibody (clone DCS-60) | WB, IP, IHC | Mouse IgG2a |
| ZG-0913F | Mouse Anti-CDKN1A Recombinant Antibody (clone WA-1) | WB, ELISA | Mouse IgG1 |
| VS3-WK744 | Mouse Anti-CDKN1A Recombinant Antibody (clone Mix-mA) | WB | Mouse IgG1 |
| VS3-XY478 | Mouse Anti-CDKN1A Recombinant Antibody (clone 2G2) | WB, IP, IF, IHC, FC | Mouse IgG1 |
Chicken IgY Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| BRD-0114MZ | Chicken Anti-CDKN1A Polyclonal IgY | WB | Chicken antibody |
Rabbit Monoclonal Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOR-0639 | Hi-Affi™ Rabbit Anti-CDKN1A Recombinant Antibody (clone DS639AB) | ICC, IHC-P, IP, WB | Rabbit IgG |
| MOR-4658 | Hi-Affi™ Rabbit Anti-CDKN1A Recombinant Antibody (clone TH172DS) | WB, IF, ICC, FC | Rabbit IgG |
| MOR-0073-FY | Rabbit Anti-CDKN1A Recombinant Antibody (clone AFY0044) | ICC, IHC-P, WB | Rabbit IgG |
MHC Tetramer for Cancer
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MHC-YF386 | A*02:01/Human Cyclin-dependent kinase 4 (ALTPVVVTL) MHC Pentamer | FCM | |
| MHC-YF387 | A*02:01/Human Cyclin-dependent kinase inhibitor 1 (FAWERVRGL) MHC Pentamer | FCM |
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For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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